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Cardio Chapter 33
Assessment and Management of Patients With Hematologic Disorders
| Question | Answer |
|---|---|
| absolute neutrophil count: | a calculation of the number of circulating neutrophils, derived from the total white blood cells (WBCs) and the percentage of neutrophils counted in a microscope’s visual field |
| anemia: | decreased red blood cell (RBC) count |
| anergy: | diminished reactivity to antigens (transient or complete) |
| angiogenesis: | formation of new blood vessels |
| angular cheilosis: | cracking sore at corner of mouth |
| aplasia: | lack of cellular development (eg, of cells within the bone marrow) |
| band cell: | slightly immature neutrophil |
| blast cell: | primitive WBC |
| cytokines: | hormones produced by leukocytes that are vital to regulation of hematopoiesis, apoptosis, and immune responses |
| D-dimer: | test to measure fibrin breakdown; considered more specific than fibrin degradation products in the diagnosis of disseminated intravascular coagulation |
| differentiation: | development of functions and characteristics that are different from those of the parent stem cell |
| erythrocyte: | see red blood cell |
| erythrocyte sedimentation rate: | laboratory test that measures the rate of settling of RBCs; elevation is indicative of inflammation; also called the “sed rate” |
| erythroid cells: | any cell that is or will become a mature RBC |
| erythropoiesis: | process of formation of RBCs |
| erythropoietin: | hormone produced primarily by the kidney; necessary for erythropoiesis |
| fibrin: | filamentous protein; basis of thrombus and blood clot |
| fibrinogen: | protein converted into fibrin to form thrombus and clot |
| fibrinolysis: | process of breakdown of fibrin clot |
| granulocyte: | granulated WBC (neutrophil, eosinophil, basophil); sometimes used synonymously with neutrophil |
| haptoglobin: | blood protein synthesized by liver; binds free hemoglobin released from erythrocytes, which is then removed by the reticuloendothelial |
| hematocrit: | percentage of total blood volume consisting of RBCs |
| hematopoiesis: | complex process of the formation and maturation of blood cells |
| hemoglobin: | iron-containing protein of RBCs; delivers oxygen to tissues |
| hemolysis: | destruction of RBCs; can occur within or outside of the vasculature |
| hemosiderin: | iron-containing pigment derived from breakdown of hemoglobin |
| hemostasis: | intricate balance between clot formation and clot dissolution |
| histiocytes: | cells present in all loose connective tissue, capable of phagocytosis |
| hypochromia: | pallor within the RBC caused by decreased hemoglobin content |
| left shift, or shift to the left: | increased release of immature forms of WBCs from the bone marrow in response to need |
| leukocyte: | see white blood cell |
| leukemia: | uncontrolled proliferation of WBCs, often immature |
| leukopenia: | less-than-normal amount of WBCs in circulation |
| lymphocyte: | form of WBC involved in immune functions |
| lymphoid: | pertaining to lymphocytes |
| lysis: | destruction of cells |
| macrophage: | reticuloendothelial cells capable of phagocytosis |
| microcytosis: | smaller-than-normal RBCs |
| monocyte: | large WBC that becomes a macrophage when it leaves the circulation and moves into body tissues |
| myeloid: | pertaining to nonlymphoid blood cells that differentiate into RBCs, platelets, macrophages, mast cells, and various WBCs |
| myelopoiesis: | formation and maturation of cells derived from myeloid stem cell |
| neutropenia: | lower-than-normal number of neutrophils |
| neutrophil: | fully mature WBC capable of phagocytosis; primary defense against bacterial infection |
| normochromic: | normal RBC color, indicating normal amount of hemoglobin |
| normocytic: | normal size of RBC |
| nucleated RBC: | immature form of RBC; portion of nucleus remains within the RBC |
| oxyhemoglobin: | combined form of oxygen and hemoglobin; found in arterial blood |
| pancytopenia: | abnormal decrease in WBCs, RBCs, and platelets |
| petechiae: | tiny capillary hemorrhages |
| phagocytosis: | process of cellular ingestion and digestion of foreign bodies |
| plasma: | liquid portion of blood plasminogen: |
| platelet: | thrombocyte; a cellular component of blood involved in blood coagulation |
| poikilocytosis: | variation in shape of RBCs |
| polycythemia: | excess RBCs |
| red blood cell (RBC): | erythrocyte; a cellular component of blood involved in the transport of oxygen and carbon dioxide |
| reticulocytes: | slightly immature RBCs, usually only 1% of total circulating RBCs |
| reticuloendothelial system: | complex system of cells throughout body capable of phagocytosis |
| serum: | portion of blood remaining after coagulation occurs |
| stem cell: | primitive cell, capable of self-replication and differentiation into myeloid or lymphoid stem cell thrombin: |
| thrombocyte: | see platelet |
| thrombocytopenia: | lower-than-normal platelet count |
| thrombocytosis: | higher-than-normal platelet count |
| white blood cell (WBC): | leukocyte; one of several cellular components of blood involved in defense of the body; subtypes include neutrophils, eosinophils, basophils, monocytes, and lymphocytessystem |