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Cardio Chapter 33
Assessment and Management of Patients With Hematologic Disorders
Question | Answer |
---|---|
absolute neutrophil count: | a calculation of the number of circulating neutrophils, derived from the total white blood cells (WBCs) and the percentage of neutrophils counted in a microscope’s visual field |
anemia: | decreased red blood cell (RBC) count |
anergy: | diminished reactivity to antigens (transient or complete) |
angiogenesis: | formation of new blood vessels |
angular cheilosis: | cracking sore at corner of mouth |
aplasia: | lack of cellular development (eg, of cells within the bone marrow) |
band cell: | slightly immature neutrophil |
blast cell: | primitive WBC |
cytokines: | hormones produced by leukocytes that are vital to regulation of hematopoiesis, apoptosis, and immune responses |
D-dimer: | test to measure fibrin breakdown; considered more specific than fibrin degradation products in the diagnosis of disseminated intravascular coagulation |
differentiation: | development of functions and characteristics that are different from those of the parent stem cell |
erythrocyte: | see red blood cell |
erythrocyte sedimentation rate: | laboratory test that measures the rate of settling of RBCs; elevation is indicative of inflammation; also called the “sed rate” |
erythroid cells: | any cell that is or will become a mature RBC |
erythropoiesis: | process of formation of RBCs |
erythropoietin: | hormone produced primarily by the kidney; necessary for erythropoiesis |
fibrin: | filamentous protein; basis of thrombus and blood clot |
fibrinogen: | protein converted into fibrin to form thrombus and clot |
fibrinolysis: | process of breakdown of fibrin clot |
granulocyte: | granulated WBC (neutrophil, eosinophil, basophil); sometimes used synonymously with neutrophil |
haptoglobin: | blood protein synthesized by liver; binds free hemoglobin released from erythrocytes, which is then removed by the reticuloendothelial |
hematocrit: | percentage of total blood volume consisting of RBCs |
hematopoiesis: | complex process of the formation and maturation of blood cells |
hemoglobin: | iron-containing protein of RBCs; delivers oxygen to tissues |
hemolysis: | destruction of RBCs; can occur within or outside of the vasculature |
hemosiderin: | iron-containing pigment derived from breakdown of hemoglobin |
hemostasis: | intricate balance between clot formation and clot dissolution |
histiocytes: | cells present in all loose connective tissue, capable of phagocytosis |
hypochromia: | pallor within the RBC caused by decreased hemoglobin content |
left shift, or shift to the left: | increased release of immature forms of WBCs from the bone marrow in response to need |
leukocyte: | see white blood cell |
leukemia: | uncontrolled proliferation of WBCs, often immature |
leukopenia: | less-than-normal amount of WBCs in circulation |
lymphocyte: | form of WBC involved in immune functions |
lymphoid: | pertaining to lymphocytes |
lysis: | destruction of cells |
macrophage: | reticuloendothelial cells capable of phagocytosis |
microcytosis: | smaller-than-normal RBCs |
monocyte: | large WBC that becomes a macrophage when it leaves the circulation and moves into body tissues |
myeloid: | pertaining to nonlymphoid blood cells that differentiate into RBCs, platelets, macrophages, mast cells, and various WBCs |
myelopoiesis: | formation and maturation of cells derived from myeloid stem cell |
neutropenia: | lower-than-normal number of neutrophils |
neutrophil: | fully mature WBC capable of phagocytosis; primary defense against bacterial infection |
normochromic: | normal RBC color, indicating normal amount of hemoglobin |
normocytic: | normal size of RBC |
nucleated RBC: | immature form of RBC; portion of nucleus remains within the RBC |
oxyhemoglobin: | combined form of oxygen and hemoglobin; found in arterial blood |
pancytopenia: | abnormal decrease in WBCs, RBCs, and platelets |
petechiae: | tiny capillary hemorrhages |
phagocytosis: | process of cellular ingestion and digestion of foreign bodies |
plasma: | liquid portion of blood plasminogen: |
platelet: | thrombocyte; a cellular component of blood involved in blood coagulation |
poikilocytosis: | variation in shape of RBCs |
polycythemia: | excess RBCs |
red blood cell (RBC): | erythrocyte; a cellular component of blood involved in the transport of oxygen and carbon dioxide |
reticulocytes: | slightly immature RBCs, usually only 1% of total circulating RBCs |
reticuloendothelial system: | complex system of cells throughout body capable of phagocytosis |
serum: | portion of blood remaining after coagulation occurs |
stem cell: | primitive cell, capable of self-replication and differentiation into myeloid or lymphoid stem cell thrombin: |
thrombocyte: | see platelet |
thrombocytopenia: | lower-than-normal platelet count |
thrombocytosis: | higher-than-normal platelet count |
white blood cell (WBC): | leukocyte; one of several cellular components of blood involved in defense of the body; subtypes include neutrophils, eosinophils, basophils, monocytes, and lymphocytessystem |