The movement of a drug from the dosage formulation to the blood.

The movement of drugs from an area of lower concentration to an area of higher concentration.

Drugs that activate receptors to accelerate or slow normal cellular function.

Drugs that bind with receptors but do not activate them.

The relative amount of an administered dose that reaches the general circulation and the rate at which this occurs.

The comparison of bioavailability between two dosage forms.

The study of the factors associated with drug products and physiological processes and the resulting systemic concentrations of drugs.

The time the drug concentration is above the MEC.

A complex protein that catalyzes chemical reactions.

The increase in hepatic enzyme activity that results in greater metabolism of drugs.

The decrease in hepatic enzyme activity that results in reduced metabolism of drugs.

first-pass metabolism

The substantial degradation of an orally administered drug caused by enzyme metabolism in the liver before the drug reaches the systemic circulation.

gastric emptying time

The time a drug will stay in the stomach before it is emptied into the small intestine.

Capable of associating with or absorbing water.

Water repelling; cannot associate with water.

The substance resulting from the body's transformation of an administered drug.

minimum effective concentration (MEC)

The blood concentration needed for a drug to produce a response.

minimum toxic concentration (MTC)

The upper limit of the therapeutic window.

The functional unit of the kidney.

The time MEC is reached and the response occurs.

The movement of drugs from an area of higher concentration to lower concentration.

pharmaceutical alternative

Drug products that contain the same active ingredient but not necessarily in the same salt form, amount, or dosage form.

pharmaceutical equivalent

Drug products that contain identical amounts of the same active ingredient in the same dosage form.

The attachment of a drug molecule to a protein, effectively making the drug inactive.

The cellular material which interacts with the drug.

The characteristic of a drug that makes its action specific to certain receptors.

The location where an administered drug produces an effect.

therapeutic equivalent

Pharmaceutical equivalents that produce the same effects in patients.

A drug's blood concentration ranges between its MEC and MTC.

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Pharm Procedures II

Pharm Proc YBI Chap 10 Terms

Question	Answer
absorption	The movement of a drug from the dosage formulation to the blood.
active transport	The movement of drugs from an area of lower concentration to an area of higher concentration.
agonists	Drugs that activate receptors to accelerate or slow normal cellular function.
antagonists	Drugs that bind with receptors but do not activate them.
bioavailability	The relative amount of an administered dose that reaches the general circulation and the rate at which this occurs.
bioequivalency	The comparison of bioavailability between two dosage forms.
biopharmaceutics	The study of the factors associated with drug products and physiological processes and the resulting systemic concentrations of drugs.
duration of action	The time the drug concentration is above the MEC.
enzyme	A complex protein that catalyzes chemical reactions.
enzyme induction	The increase in hepatic enzyme activity that results in greater metabolism of drugs.
enzyme inhibition	The decrease in hepatic enzyme activity that results in reduced metabolism of drugs.
first-pass metabolism	The substantial degradation of an orally administered drug caused by enzyme metabolism in the liver before the drug reaches the systemic circulation.
gastric emptying time	The time a drug will stay in the stomach before it is emptied into the small intestine.
hydrophilic	Capable of associating with or absorbing water.
hydrophobic	Water repelling; cannot associate with water.
lipoidal	Fat-like substance.
metabolite	The substance resulting from the body's transformation of an administered drug.
minimum effective concentration (MEC)	The blood concentration needed for a drug to produce a response.
minimum toxic concentration (MTC)	The upper limit of the therapeutic window.
nephron	The functional unit of the kidney.
onset of action	The time MEC is reached and the response occurs.
passive diffusion	The movement of drugs from an area of higher concentration to lower concentration.
pharmaceutical alternative	Drug products that contain the same active ingredient but not necessarily in the same salt form, amount, or dosage form.
pharmaceutical equivalent	Drug products that contain identical amounts of the same active ingredient in the same dosage form.
protein binding	The attachment of a drug molecule to a protein, effectively making the drug inactive.
receptor	The cellular material which interacts with the drug.
selective (action)	The characteristic of a drug that makes its action specific to certain receptors.
site of action	The location where an administered drug produces an effect.
therapeutic equivalent	Pharmaceutical equivalents that produce the same effects in patients.
therapeutic window	A drug's blood concentration ranges between its MEC and MTC.

Created by: dsljulian

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