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Receptors and effect
Lecture 8
| Receptor | Effect |
|---|---|
| D2 receptor: | Extrapyramidal Syndromes (EPS) |
| D2 receptor: | Dystonia |
| D2 receptor: | Akathisia |
| D2 receptor: | Parkinsonism |
| D2 receptor: | Tardive Dyskinesia |
| D2 receptor: | Neuroleptic Malignant Syndrowme (NMS) (altered mental status, motor symptoms, hyperthermia, autonomic instability) |
| α1-adrenergic receptor: | Hypotension |
| H1 receptor: | Increased appetite |
| Muscarinic receptor: | Anticholinergic |
| Serotonin receptor 5HT2A: | Decreased anxiety Helps with sleep (benefit) |
| Fast sodium channel: | Cardiac problems Increased QRS |
| GABAA receptor: | Seizures Don't see very often |