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HIT 226 Ch. 3
Principles of Disease
| Question | Answer |
|---|---|
| new growth | neoplasm |
| a swelling or a neoplasm | tumor |
| Not all neoplasms form tumors. | True |
| a malignant disease of the bone marrow that causes an increase in white blood cell production and might not form distinctive tumor | leukemia |
| a large tumor or swelling filled with blood; commonly called a bruise or contusion | hematoma |
| 1) Appearance and growth pattern 2) Tissue of origin, or type of body tissue from which they grow | 2 ways to classify neoplasms |
| neoplasms that are confined to a local area and do not spread | benign |
| exhibit characteristics of invasion and metastasis | malignant |
| the spreading of the neoplasm into local or surrounding tissue | invasion |
| the spread of the neoplasm to distant sites | metastasis |
| the most common type of malignant neoplasm arising from epithelial tissue | carcinoma |
| a malignant neoplasm arising from connective tissue | sarcoma |
| Neoplasms are classified or named according to the tissue from which they grow along with the suffix "oma" for tumor. | True |
| A benign tumor of epithelial tissue such as a gland would be adenoma | True |
| If it is a malignant neoplasm, the name becomes adenocarcinoma. | True |
| malignant neoplasms of lymphatic and blood-forming organs and lymphatic tissues | lymphomas |
| glandular epithelium | benign - adenoma malignant - adenocarcinoma |
| squamous epithelium | benign - epithelioma malignant - squamous cell carcinoma |
| adipose | benign - lipoma malignant - liposarcoma |
| cartilage | benign - chondroma malignant - chondrosarcoma |
| bone | benign - osteoma malignant - osteosarcoma |
| glial | only malignant - glioma |
| blood | only malignant - leukemia |
| the process of individual specialization | differentiation |
| vessel growth or new growth of blood vessels | angiogenesis |
| an individual begins to lose weight and appear thin, frail, and weak | cachexia |
| overgrowth of cells that cause an increase in the size of the tissue | hyperplasia |
| Hyperplasia usually occurs in response to a stimulus, and the growth stops when the stimulus stops | True |
| Neoplasms are not only an increase in cell number, but new or different in their appearance from their cell of origin, or mother | True |
| cancer-causing agent or substance | carcinogen |
| the process of using light, short waves such as ultraviolet or x-ray | radiation |
| abnormal hyperplasia | dysplasia |
| atypical cells are "just sitting" in the epithelial layer of the tissue and have not broken through the basement membrane and invaded the surrounding tissue | carcinoma in situ |
| Sarcomas do not use the lymphatic system as readily as carcinomas. | True |
| determines the degree of differentiation of the neoplasm | grading |
| considers the degree of spread | staging |
| undifferentiated | neoplastic |
| The higher the degree of differentiation, the better the prognosis. | True |
| removing a small piece of tissue for microscopic examination | biopsy |
| Grading and staging are two predictors of prognosis; staging is the better indicator. | True |
| cancer development | cardinogenesis |
| a cellular adaptation in which the cell changes to another type of cell | metaplasia |
| a test to screen for cervical cancer | pap test |
| Change in bowel or bladder habits A sore that does not heal Unusual bleeding or discharge Thickening or lump in breast Indigestion or difficulty swallowing Obvious change in a wart or mole Nagging cough or hoarseness | CAUTION |
| examination of cells | cytology |
| a technique that enables the pathologist to make a rapid determination of the tumor condition: benign or malignant | frozen section |
| using pharmacologic therapy in the treatment of cancer | chemotherapy |
| treatment aimed and curing | curative |
| treatment to relieve symptoms | palliative |