click below
click below
Normal Size Small Size show me how
Choosing controls
Question | Answer |
---|---|
What are the three ways of choosing controls? | 1) Nested case control 2) Case-cohort or case-base sampling 3) Risk-set sampling or density sampling |
How are controls selected from a nested case-control study? | Controls are selected from those who do not experience the outcome during follow-up of a cohort study. |
Controls selected using which method gives an estimate of exposure odds of the survivors? | Nested case-control |
What does the exposure odds of survivors estimate? | OR in the base population |
How are controls selected using case-cohort or case-base sampling? | Controls are selected from entire base population (those at-risk at beginning of follow-up) |
Controls selected using which method gives an estimate of exposure odds in the base population of person at risk at start of followup? | Case-cohort or case-base sampling |
What does the exposure odds in the base population of person at risk at start of followup estimate? | Risk ratio in the base population |
How are controls selected using risk-set sampling or density sampling? | Controls are selected longitudinally throughout the course of the study. |
Controls selected using which method gives an estimate of exposure odds in the study base (i.e., person-time at risk)? | Risk-set sampling or density sampling |
What does the exposure odds in the study base (i.e., person-time at risk) estimate? | Rate ratio in the base population |
Which method of selecting controls is used in most case-control studies? | Density sapling (with matching on a time variable such as calendar time or age) and thus estimate the rate ratio without the need for any rare disease assumption. |