Lab Animal
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| What is the average lifespan of a mouse? | 2-3 years
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| At what age do mice reproduce? | 6 weeks of age
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| What is the most commonly used species of mice? | Mus musculus
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| What term refers to animals that are born hairless, eyes closed and mouth closed? HINT: Pinkes* | Altricial
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| What is the most common parasite seen with mice? | Pin worms
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| How many teeth do mice have? | 16
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| How long is the average gestation period in the mouse? | 19-21 days
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| How large is an average mice litter? | 12-14 avg (Range 1-20)
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| What is the pH of urine from a mouse? | 7.3-8.5 HIGHLY CONCENTRATED
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| What is the average pulse rate of a mouse? | 325-780 BPM
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| What is the average respiratory rate of a mouse? | 60-220 BPM
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| What is the average temp of a mouse? | 97.5-100.4 F
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| Around what age do mice begin to wean? | 3-4 weeks
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| How long is the estrous cycle of a mouse? | 4-5 days
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| Mice reproduce via a ____________ that persists for ________________ hours. | plug, 18-24 hours
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| How long is the breed duration of mice? | 7-9 months
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| What is another name for the "Frizzie" mouse? | Rex
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| What is the most common type of mouse used in lab? | albino mouse
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| What part of it's body does the mouse use for movement and guidance? MED TERM | Vibrissae
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| What structure position behind the eyes of a mouse produces "Blood Tears" when the animal is ill? | harderian gland
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| What is the name of the 5th undeveloped finger on the mouse's forpaw? | pollex
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| True or false. When sexing a mouse, a shorter ano-genital distance lets you know the mice is a male. | False. Female
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| What is the dental formula of a mouse? | 2(I 1/1, M 3/3) 16 total
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| Abscesses in the lymph nodes of a mouse is common with what respiratory disease? | mycoplama pulmosis
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| What is the #1 disease found in Mice? | Mycoplasma pulmosis
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| How many pairs of mammary glands do male and female mice have? | 5
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| How are injections given to mice? | IP Intraperitoneal
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| What is the family that Mus musculus stems from? | Muridae
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| What is the subfamily that Mus musculus stems from? | Murinae
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| What is the Order that the Mus musculus stems from? | Rodentia
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| True or false. Mice have no sweat glands. | True
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| What temperature should a mouse's environment be? | 64-79 degrees
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| What humidity should a mouse's environment be? | 30-70%
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| What is the ratio for maintenance light requirements for a mouse? | 12:12
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| What is the ratio for breeding light requirements for a mouse? | 14:10
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| What are the 3 purposes of bedding? | absorbs waste, insulates and used to make nests
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| What percentage of protein should be included in a mouse's diet? | 23%
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| What percentage of fat should be included in a mouse's diet? | 6.5%
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| What percentage of ash should be included in a mouse's diet? | 8%
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| What is the recommended amount of food for a single mouse? | 4-5g or 1-2 pellets
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| True or false. Tumor development in mice is considered normal. | true
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| When setting up breeding cages what is the male to female ratio? | 1 male to 2-6 females
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| At what age should pups be seperated? | 1 month
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| How soon after birth can tail clipping be done? | 18 days
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| What are various methods of numbering mice? | ear notching, ear tags, tail clip or toe clip
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| How much blood can be collected from the tail of a mouse? | 0.1ml
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| How much blood can be collected from the orbital sinus of a mouse? | 0.5ml
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| How much blood can be collected from the heart of a mouse? | 1ml
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| What site is useful for collecting multiple blood samples throughout the day? | saphenous
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| What is the max amt of fluids that can be given to a mouse in a single dose via IP? | 2ml
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| How do you determine the amt to feed orally in mice? | 1% of body wt
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| When sexing mice/rats which sex has a greater urogenital distance? | male
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| What is MRM? | Murine respiratory mycoplasmosis
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| What is the causitive agent of MRM? | mycoplasma pulmonis
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| What is the most common disease in pocket pets? | MRM
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| What condition is also referred to as "Proximal airway disease"? | MRM
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| What is the medical name for blood tears? | porphyrin staining
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| What condition involves cobblestone lesions on the lungs? | MRM
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| How is MRM diagnosed? | IFA and ELISA
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| What are the 2 most common forms of treatment for MRM? | tetracycline or baytril
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| What is the causitive agent of tyzzers disease? | clostridium piliforme
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| What condition includes CS such as lethargy, ruffled fur and diarrhea, and is caused by clostridium piliforme? | Tyzzers dz
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| True or false. Rats are affected more often than mice by Tyzzer's dz. | False (Mice more)
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| How is Tyzzer's transmitted? | direct
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| What condition will one see pale foci from liver necrosis? | Tyzzers dz
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| What is the TOC for Tyzzers? | oxytetracycline
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| What is the formula for drug calculation? | (wt (kg) X dosage)/conc in ml
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| What are the 2 common types of salmonella? | enteritis and typhimurium
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| What type of bacteria is salmonella? | gram neg bacillus
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| CS of salmonella are most common in what age group of mice? | suckling and weanlings
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| Pale foci on the liver, spleenomegaly AND increased neutrophils are commonly found in this disease | salmonella
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| What is the primary method of transmission for S. aureus? | fights/scratching
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| What is the major pathogen of the skin of rats and mice? | S. Aureus
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| What disease will you commonly see pyoderma and ulcerative dermatitis as well as abscesses or granulomas affecting the face and tail base? | S. Aureus
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| What is used to treat S Aureus? | nolvasan
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| What virus is associated with coronavirus and is the most common virus found in lab animals? | SDAV - Sendai Virus
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| How long is the incubation period of SDAV? | 1 week
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| What is the first sign of SDAV? | porphyrin eye staining
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| What condition will one see submandibular salivary glands red/atelectatic lungs in mice? | SDAV
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| Define atelectatic. | collapsed lung
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| What condition is the mouse the only natural host of and usually lasts for 2-3 weeks? | MHV - Mouse hepatitis virus
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| What age group will you most commonly see MHV in? | Young nursing pups
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| How is MHV diagnosed? | ELISA
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| Define EDIM. | Epizootic diarrhea of infant mice
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| What condition commonly affects mice from birth to 17 days old and causes yellow/watery diarrhea? | rotavirus
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| What type of mite is typically found on the back of the head and back? | myobia musculi
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| What type of mite has 2 claws? | radfordia affinis
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| Define acariasis. | Mite infestation
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| What rare species of mite has more than 3 claws? | Myocoptes musculinus
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| What is the best method for testing for pinworms? | tapetest
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| What type of pinworms is found ONLY in fecal floats? | aspiculuris tetraptera
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| What type of pinworms is found ONLY by the tape test method due to a collection of eggs surrounding the anus and are banana shape? | syphacia obvelata
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| What is the most common type of pinworm? | syphacia obvelata
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| What are the 2 common type of tapeworms in pet mice? | rodentolepis nana and hymenolepsis diminuta
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| What type of tapeworm has polar filaments is zoonotic? | rodentolepsis nana
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| What is the most common type of tumor in mice? | mammary adenocarcinoma
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| What is the prognosis for mammary adenocarcinoma in mice? | poor, very invasive
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| What behavioral problem commonly involves alopecia on the head without lesions? | barbering
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| Where are bite wounds in mice most commonly found? | face, genitals and back
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| What condition are mice genetically predisposed to and can cause starvation due to pain? | malocclusion
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| What species of rat is most commonly used in lab animals? | rattus norvegicus
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| What are the 2 most common types of norway rats? | wild and albino
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| What rat species is the black rat? | rattus rattus
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| What is the most common outbred rat stock? | sprague dawley
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| What rat stock is also referred to as the hooded rat? | long evans
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| What type of skeleton involves the mandible, vertebra and ribs? | axial
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| What type of skeleton involves the limbs and pelvis? | appendicular
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| What is the shared dental formula of rats and mice? | 2 (I 1/1 C 0/0 P 0/0 M 3/3)
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| What feature of a rat is thermogenic and allows rats to survive days without eating? | brown fat
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| What are the 2 primary functions of brown fat? | stores glycogen and regulates temperature
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| What part of the stomach prevents vomiting in the rat? | limiting ridge
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| True or false. Rats have gallbladders. | False
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| True or false. The stomach of a rat is glandular. | False (Part glandular, part nonglandular)
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| What vitamin is contained in rat/mice feces that is produced by bacterial action in the colon? | vitamin b
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| How many pairs of mammary glands do rats have? | 6
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| How long is the estrous cycle in rats? | 4-5 days
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| How long is the gestation of a rat? | 19-23 days
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| What is the average litter size of a rat? | 6-12
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| What is the name for the phenomenon of coming into heat shortly after giving birth? | postpartum estrus
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| What is the lifespan of a rat? | 2.5-3 years
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| True or false. Rats are nocturnal. | True
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| True or false. Female rats are more sociable than male rats. | false
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| What condition is prevented in rats by keeping the humidity greater than 40%? | ringtail
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| How much blood can be collected from the tail vein of a rat? | 0.1-1ml
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| What part of the body of a rat is used to regulate body temp by dilating and constricting of vessels? | tail
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| What veins in the tail are used for blood collection? | lateral
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| How much blood can be collected via a cardiac stick in a rat? | 3% of the body wt
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| How do you determine the amount of food that can be fed orally to a rat? | 1% of body wt
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| What are the 3 factors for determining proper dosage? | age, sensitivity and route
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| What 3 medications are used for chemical restraint in rats/mice and are not a type of anesthesia? | acepromazine, diazepam and fentanyl/droperidol.
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| What medication is used as a premed to reduce saliva/fluid production and to maintain heart rate? | anticholinergics
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| What is the most commonly used anticholinergic used in mice and rats? | glycopyrrolate
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| What cocktail is used to restrain rats/mice and has a short duration of action of 30 minutes? | xylazine/ketamine
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| What cocktail is used for minor surgical procedures and usually has a prolonged recovery? | tilazol
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| What cocktail is known as tilazol? | tiletamine/zolazepam
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| What medication is used with tilazol to increase recovery rate? | xylazine
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| What is the inhalant anesthesia of choice in mice and rats? | isoflurane
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| What strand of strep is commonly found in rats that humans are the primary reservoir for? | streptococcus pneumoniae
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| S. Pneumoniae commonly affects which age group of rats? | young
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| S. Pneumoniae clinical signs resemble what condition in rats? | URT infection
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| What are the 3 pathologic findings of S. Pneumoniae? | fibrinopurulent pleuritis, pericarditis and otitis media
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| What is used to treat rat bite fever? | penicillin
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| What is the causitive agent for Rat Bite Fever? | Streptobacillus moniliformis
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| True or false. Haverhill is zoonotic. | True
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| What condition is known as "Haverhill"? | rat bite fever
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| True or false. Diarrhea is commonly found in rats with Tyzzers. | False (Mice)
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| Dermatitis is commonly found on what parts of the body of a rat? | face, head and back of head.
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| Photophobia and sniffling/nasal crackles are commonly found with what virus? | SDAV
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| What is SDAV? | Sialodacryoadenitis virus
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| How long should breeding be ceased for when treating SDAV in rats? | 2 months
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| What is RMV and what type of virus is it? | Rat minute virus; parvovirus
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| What is the only parvo virus strand reported to cause clinical disease in rats? | RV (Rat Virus)
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| What species of mite is known as the "Rat Fur Mite"? | Radfordia ensifera
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| What species is also known as the rat pinworm? | Syphacia muris
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| What is the TOC for rat winworms? | Piperazine
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| What is the most common tumor found in rats? | mammary fibroadenoma
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| True or false. Mammary fibroadenoma found in rats is almost always benign. | True
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| Define ptyalism. | Slobbering
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| Hyperemic scrotum is pathognomonic of what condition in rats? | Heat exhaustion
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| What is the primary cause of ringtail in rats? | low environmental humidity
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| What is the only known strain of parvo virus that affects rats? | Rat Virus
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| True or false. Male pinworms are larger than female pinworms. | False
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| What is the main sign seen with pituitary chromophobe adenoma? | prolactin secretion
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