420 DRUGS PART 2
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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| show | Muscarinic Agonists
Quaternary amine
USE: urinary retention/ileus
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| show | Muscarinic Agonists
Quaternary amine and non-selective muscarinic and nicotinic agonist
USE: Glaucoma
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| Cevimeline (Evoxac) | show 🗑
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| show | Muscarinic Agonists
Tertiary amine
USE: Sjogren's (dry mouth), glaucoma
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| show | AChE inhibitors reversible
USE: Urinary retention/ileus, myasthenia gravis
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| Physostigmiine (Eserine-generic) | show 🗑
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| show | AChE inhibitor reversible
USE: myasthenia gravis
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| Edrophonium (Tensilon) | show 🗑
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| Difluorophosphate-DFP (Floropryl) | show 🗑
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| Echothiphate (Phospholine) | show 🗑
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| show | AChE inhibitors irreversible (cholinergic poisons, nerve gases)
5 hours before permanent
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| Tabun | show 🗑
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| show | AChE inhibitors irreversible (cholinergic poisons, nerve gases)
2 min before permanent
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| Malathion | show 🗑
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| show | Nicotinic a4b2 partial agonist
USE: smoking cessation aid
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| show | Nicotine receptor agonist
USE: smoking cessation
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| show | Anticholinergic
USE: asthma, COPD: decrease bronchial contraction and secretions
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| Tiotropium (Spiriva) | show 🗑
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| show | Anticholinergic
USE: pre-op antisecretory
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| Atropine (AtroPen) | show 🗑
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| show | Anticholinergic
USE: bradycardia, asystole: reduce dominant PNS tone-> dominant SNS tone (increase heart rate)
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| Darifenacin (Enablex) | show 🗑
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| Fesoterodine (Toviaz) | show 🗑
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| Oxybutynin (Ditropan) | show 🗑
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| Solfenacin (Vesicare) | show 🗑
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| show | Anticholinergic
USE: urinary incontinence: relax detrusor/contract internal sphincter
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| Trospium (Sanctura) | show 🗑
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| show | Anticholinergic
USE: GI hypermotility and secretions
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| show | Anticholinergic
USE: GI hypermotility and secretions and infant colic
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| Methscopolamine (Pamine) | show 🗑
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| Propantheline (Pro-Banthine) | show 🗑
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| show | Anticholinergic
USE: motion sickness: decrease excessive stimulation of vestibular pathway
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| Homoatropine (Isopto Homatropine) | show 🗑
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| Cyclopentolate (Cyclogyl) | show 🗑
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| show | Anticholinergic
USE: mydriatic: to facilitate eye exam
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| Ondansetron (Zofran) | show 🗑
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| Dolasetron (Anzemet) | show 🗑
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| Granisetron (Kytril) | show 🗑
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| Palolosetron (Aloxi) | show 🗑
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| Alosetron (Lotronex) | show 🗑
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| show | USE: abortive therapy of mild migrane
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| Barbiturate hypnotics: butalbital/ASA/caffeine | show 🗑
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| Triptans | show 🗑
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| Ergotamine tartrate (Ergomar)SL tablets | show 🗑
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| Dihydroergotamine D.H.E (Migranal, D.H.E. 45) | show 🗑
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| show | Ergot Alkaloids
USE: prevention and treatment of postpartum atony and hemorrhage
MOA: agonist/antagonist of a1 and 5-HT2 receptors--> strong contractions of uterus --> compress uterine blood vessels
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| show | Ergot Alkaloids
USE: prevention and treatment of postpartum atony and hemorrhage
MOA: agonist/antagonist of a1 and 5-HT2 receptors--> strong contractions of uterus --> compress uterine blood vessels
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| Citalopram (Celexa) | show 🗑
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| show | Selective Serotonin Reuptake Inhibitors (SSRIs)
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| Fluoxetine (Prozac, Sarafem) | show 🗑
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| show | Selective Serotonin Reuptake Inhibitors (SSRIs)
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| show | Selective Serotonin Reuptake Inhibitors (SSRIs)
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| Sertraline (Zoloft) | show 🗑
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| Venlaflaxine (Effexor) | show 🗑
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| show | Serotonin/NE Reuptake Inhibitors (SNRIs)
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| Duloxetine (Cymbalta) | show 🗑
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| show | Serotonin/NE Reuptake Inhibitors (SNRIs)
USE: fibromyalgia
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| Mephobarbital (Mebaral) | show 🗑
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| show | Barbiturate
USE: sedative, hypnotic, anticonvulsant
ONSET: 60 min DURATION: 15 hrs (long)
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| show | Barbiturate
USE: sedative, hypnotic
ONSET: 60 min DURATION: 8 hrs (intermediate)
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| Pentobarbital (Nembutal) | show 🗑
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| show | Barbiturate
USE: insomnia, pre-anesthesia
ONSET: 15 min DURATION: 4 hrs (short)
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| Thiopental (Pentothal) | show 🗑
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| show | Benzodiazepine
USE: anxiety, preanesthesia, alcohol withdrawl
ONSET: 40 min DURATION: 24-48 hrs (long)
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| Clonazepam (Klonopin) | show 🗑
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| Diazepam (Valium) | show 🗑
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| Alprazolam (Xanax) | show 🗑
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| show | Benzodiazepine
USE: anxiety, preanesthesia, status epilepticus, alcohol withdrawal, preanesthesia, amnesia
ONSET: 12 min DURATION: 12-18 hrs (short)
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| Oxazepam (Serax) | show 🗑
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| Temazepam (Restoril) | show 🗑
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| show | Benzodiazepine
USE: Preanesthesia, amnesia, induce/maintain anesthesia
ONSET: 4 min DURATION: <6 hr (ultrashort)
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| Triazolam (Halcion) | show 🗑
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| show | USE: anxiety
ONSET of efficacy is 1-2 weeks
MOA: serotonin receptor agonist, no effect on GABA receptor or GABA binding to GABA receptor
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| Eszopiclone (Lunesta) | show 🗑
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| show | Non-BDZs Hypnotics
USE: insomnia
MOA: agonist of BZ1 (omega1 receptor)
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| show | Non-BDZs Hypnotics
USE: insomnia
MOA: agonist of BZ1 (omega1 receptor)
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| show | Non-BDZs Hypnotic
USE: insomnia
MOA: agonist of melatonin receptors of suprachiasmatic nuclei= maintain carcadian rhythm or normal sleep-wake cycle
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| show | Miscellaneous Older CNS depressants
USE: preop: anti-anxiety and sedation, postop: adjunct to opiates and other analgesics, hypnotic: loses effectiveness after 2 week therapy, prevent or suppress alcohol withdrawal symptoms
MOA: unknown
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| show | Miscellaneous Older CNS depressants
USE: anxiety (reduced efficacy after 4 months)
MOA: unknown
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| show | MOA: binds to different site on GABA receptor, inhibits activation of NMDA (excitory) receptors, effects on other channels and neurotransmitters
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| show | Miscellaneous Older CNS depressants
USE: treatment of alcohol abuse
MOA: cause acetaldehyde poisoning- inhibit ALDH-increase in acetaldehyde- vasodillation, intense throbbing headache, vomitting, sweating, vertigo, blurred vision, weakness, confusion
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| Phenobarbital | show 🗑
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| Phenytoin (Dilantin) | show 🗑
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| show | Older AED
USE: Simple&Complex Partial, Grand Mal, Absence, Status
MOA: block Na and Ca channels, increase GABA levels
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| Primidone (Mysoline) | show 🗑
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| show | Older AED
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| Levetiracetam (Keppra) | show 🗑
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| Lamotrigine (Lamictal) | show 🗑
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| show | Newer AED
USE: Simple&Complex Partial
MOA: block Ca channels, increase GABA release, decreaase glutamate release
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| Gabapentin (Neurontin) | show 🗑
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| Topiramate (Topamax) | show 🗑
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| show | USE: maintain alcohol abstinence
MOA: restore balance of GABA and glutamate activity, enhance action of GABA at GABA receptors, reduce neuronal hyper-excitability during alcohol withdrawl
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Created by:
lmcajigal
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