exam 8
Quiz yourself by thinking what should be in
each of the black spaces below before clicking
on it to display the answer.
Help!
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what general receptor type stimulates heart activity | show 🗑
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show | M2 receptors. parasympathetic
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skin, renal, and splanchnic smooth muscle constricts via activation of what receptor (sympathetic) | show 🗑
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show | B2
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skeletal muscle constricts via activation of what receptor (sympathetic) | show 🗑
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amount of Ca released during an AP is based on what | show 🗑
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how long does cross bridging during an AP last | show 🗑
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when does relaxation occur during AP | show 🗑
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show | amount of intracellular [Ca]
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show | use of hormones, NT, and drugs that:
1. alter inward Ca current during AP
2.Alter SR Ca stores
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show | pressure in aorta
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afterload | show 🗑
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Homeometric regulation | show 🗑
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show | Frank-Starling relationship. dependent on fiber length
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stroke volume | show 🗑
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show | End diastolic volume- end systolic volume
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ejection fraction | show 🗑
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ejection fraction equation | show 🗑
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Cardiac output | show 🗑
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cardiac output equation | show 🗑
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voltage effect | show 🗑
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show | premature depolarization. increase Ca. when next beat comes along more Ca than normal. Results in more forceful beat (Postestrasystole)
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show | 1.poisons Na/K pump
2.used to increase cardiac force of contraction.
Tension directly proportional to intracellular Ca
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show | Increase length, increase force of contraction
1.increase muscle length, increase Ca sensitivity to troponin C
2. increase muscle length, increase Ca release in SR
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show | 2.2u
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show | 1.6u
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show | isovolumetric contraction
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Ventricular pressure volume loop: 2-3 | show 🗑
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Ventricular pressure volume loop:3-4 | show 🗑
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show | refilling phase. relaxed
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P-V loop: increased preload | show 🗑
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show | increased aortic pressure. decrease stroke volume. increase end systolic volume
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P-V loop: increased contractility | show 🗑
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show | increase O2 consumption. increase wall thickness (protection) therefore decrease overall tension. maintain normal O2 consumption and prevent O2 deficiency
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show | Atrial systole. atria contract. final phase of ventricular filling
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show | isovolumetic ventricular contraction. mitral valve closes
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2nd heart sound associated with | show 🗑
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show | rapid ventricular filling. mitral valve heart opens
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show | respond to specific chemical changes in CO2, O2, and pH
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show | high pressure sensors.
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show | 1.sensors of BP
2.afferent neurons. info to brainstem
3.brain stem centers
4.efferent neurons. direct change in heart and blood vessels
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ADH V1 receptor | show 🗑
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ADH V2 receptor | show 🗑
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ADH secretion stim when | show 🗑
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show | located in veins, atria, pulmonary arteries. sense change in blood volume
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Low pressure baroreceptor response to increased BV | show 🗑
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show | secreted by atria. binds ANP receptors on vasculature smooth muscle. promotes relaxation, vasodilation, and decrease TPR
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outcome of general sympathetic regulation | show 🗑
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show | 1. decreased HR
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show | Na and H2O reabsorption
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outcome of ADH | show 🗑
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show | Increase Na, and H2O excretion (increase vascular permeability)
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starling law of capillar | show 🗑
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Kf | show 🗑
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what is kf influenced by | show 🗑
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show | 1.change in arteriolar resistance
2.hypoxia
3.build up of metabolites
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show | capillary hydrostatic pressure. force favoring filtration out of capillary.
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show | arterial and venous pressure. more affected by change in venous pressure
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Pi | show 🗑
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PiC | show 🗑
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show | interstitial oncotic pressure. force favoring filtration. near zero
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show | 1.increase filtration
2.increase Pc. increase in arterial pressure or venous pressure
3.decrease PiC. dilution of plasma [protein]
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show | 1.coronary
2.cerebral
3.pulmonary
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show | 1.renal
2.skin
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coronary circulation regulation sp. metabolites | show 🗑
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show | CO2
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pulomary circulation regulation sp. metabolites | show 🗑
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show | sympathetic. a1 receptors increase
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Skeletal muscle circulation regulation during exercise | show 🗑
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show | increase sympathetic outflow
1.increase HR (increase cardiac output)
2.Increase contractility
3.constriction of arterioles
4.constriction of veins
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show | increase angiotenin II
1.increase TPR
2.increase aldosterone
3.increase Na reabsorption
4.increase BV
5.increase stress volume
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show | change in starling.
Decrease Pc
1.increase fluid absorption
2. increase blood volume
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