Neurotransmitters and Neuropharmacology (Ch 4)
Help!
|
|
||||
|---|---|---|---|---|---|
| Amine Neurotransmitters | Neurotransmitter based on modifications of a single amino acid nucleus. (acetylcholine,serotonin, dopamine)
🗑
|
||||
| Amino Acid Neurotransmitter | A neurotransmitter that is itself an amino acid (GABA, glycine, glutamate)
🗑
|
||||
| Peptide Neurotransmitter | A neurotransmitter consisting of a short chain of amino acids
🗑
|
||||
| Gas Neurotransmitter | A soluble gas that is produced and released by a neuron to alter the functioning of another neuron
🗑
|
||||
| Ionotropic Receptor (fast) | A receptor protein that include an ion channel that is opened when the receptor is bound by an agonist
🗑
|
||||
| Metabolic Receptor (slow) | A receptor protein that does not contain an ion channel but may when activated use a G protein system to open a nearby ion channel
🗑
|
||||
| Ligand | A substance that binds to a receptor
🗑
|
||||
| Agonist | A molecule that binds to a receptor molecule and initiates a response
🗑
|
||||
| Antagonist | A molecule that interferes with or prevents the action of a transmitter
🗑
|
||||
| Inverse Antagonist | A substance that binds to a receptor and causes it to do the opposite of what the naturally occurring transmitter does
🗑
|
||||
| Endogenous Ligands | Produced inside the body
🗑
|
||||
| Exogenous Ligands | Arising from outside the body
🗑
|
||||
| Co-Localization/Co-Release | The appearance of more than one neurotransmitter in a given presynaptic terminal
🗑
|
||||
| Cholinergic | Referring to cells that use ACh as their synaptic transmitter
🗑
|
||||
| Nicotinic | Referring to cholinergic receptors that respond to nicotine AND ACh
🗑
|
||||
| Muscarinic | Referring to cholinergic receptors that respond to mucsarine AND ACh
🗑
|
||||
| 5 monoamines | Catecholamines, indoleamines, dopamine, norepinephrine, serotonin
🗑
|
||||
| Excitotoxicity | The property by which neurons die when overstimulated
🗑
|
||||
| Retrograde Transmitter | A neurotransmitter that diffuses from the postsynaptic neuron to the presynaptic neuron
🗑
|
||||
| Affinity | The degree of chemical attraction between a ligand and a receptor
🗑
|
||||
| Efficacy/intrinsic activity | The extent to which a drug activates a response when it binds to a receptor
🗑
|
||||
| Partial Agonist/Partial Antagonist | A drug that when bound to a receptor has less effect than the endogenous ligand
🗑
|
||||
| Modulatory Site | A portion of a receptor that when bound by a compound alters the receptors response to it's transmitter. Binds to a site different than the transmitter site
🗑
|
||||
| Metabolic tolerance | THe form of drug tolerance that arises when repeated exposure to the drug causes the metabolic machinery (liver, etc) of the body to become more efficient at clearing the drug
🗑
|
||||
| Functional tolerance | decreased responding to a drug after repeated exposures (brain tissue doesn't respond anymore)
🗑
|
||||
| Cross tolerance | A condition in which the development of tolerance for one drug causes an individual to develop tolerance to another drug
🗑
|
||||
| Sensitization | A process in which the body shows an enhanced response to a given drug after repeated doses
🗑
|
Review the information in the table. When you are ready to quiz yourself you can hide individual columns or the entire table. Then you can click on the empty cells to reveal the answer. Try to recall what will be displayed before clicking the empty cell.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
To hide a column, click on the column name.
To hide the entire table, click on the "Hide All" button.
You may also shuffle the rows of the table by clicking on the "Shuffle" button.
Or sort by any of the columns using the down arrow next to any column heading.
If you know all the data on any row, you can temporarily remove it by tapping the trash can to the right of the row.
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.
Normal Size Small Size show me how
Normal Size Small Size show me how
Created by:
586065465
Popular Neuroscience sets