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Pharm-Aminoglyco.

Aminoglycosides

QuestionAnswer
Aminoglycosides have the potential to cause serious side effects such as: nephrotoxicity, ototoxicity and neuromuscular
Aminoglycosides Clinical Uses: Pneumonia, endometritis, UTI's, skin and soft tissue infections, pseudomonas infection in ears
Aminoglycosides are compounds containing what? amino sugars
Examples of Aminoglycosides: Streptomycin, Pen/Strep, Dihydrostreptomycin (LA), Neomycin, Kanamycin, Gentamycin, Tritop, Otomax, Amikacin
Aminoglycosides Spectrum of activity: Broad but primarily used against Gram -
Aminoglycosides Toxicity High potential
Aminoglycosides are especially effective against what organism? Pseudomonas
What are the two main possible toxic side effects from aminoglycosides? Nephrotoxicity and Ototoxicity
When are Aminoglycosides contraindicated? Renal insufficiency and food producing animals
Aminoglycosides Forms Parenteral, poor oral absorption, topical drops and ointments
Aminoglycosides Stability Very Stable
Aminoglycosides Resistance Variable - streptomycin and dihydrostreptomycin resistances
Which Aminoglycoside is used against TB, tularemia and Gram -? Dihydrostreptomycin
What Aminoglycosides form is used to treat birds and equine metritis? Amikacin
What Aminoglycosides form is toxic to birds? Gentamicin
What Aminoglycoside is used off label with injectable used topically in ears for pseudomonas? Amikacin
Created by: k.jamie9