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Pharm-Tetracyclines
Tetracyclines
| Question | Answer |
|---|---|
| Tetracyclines clinical uses/indications | Respiratory infections, dental disease, bacterial enteritis and UTI’s |
| Tetracyclines Spectrum of Activity | Broad - Gram +, Gram - and rickettsial |
| What Tetracyclines dosage form is used to treat Lyme disease, ehrlichiosis and rickettsial organisms? | Doxycycline |
| Tetracyclines Toxicity | Non-toxic |
| Tetracyclines Side effects | v/d |
| Tetracyclines Administration | PO, parenterally or topically |
| Tetracyclines Stability | Stable - needs to be kept cool |
| Tetracyclines -static or -cidal | Bacteriostatic |
| Tetracyclines Resistance | Increasing over time |
| Tetracyclines Contraindications | Causes permanent yellow discoloration of teeth; not absorbed from GI if given with milk or antacids |
| Tetracyclines Excretion | Kidneys |
| Tetracyclines Metabolism | Very little metabolism in liver = EXCRETED IN THE ACTIVE FORM |
| Tetracyclines Dosage forms | Tetracycline hydrochloric/Panmycin, Ocytetracycline/Terramycin, chlortetracycline/Aureomycin (LA), Doxycycline/Doxirobe |
| Doxirobe gel is used to treat what condition? | Periodontal disease |
| What are Tetracyclines effective against besides bacterial organisms? | rickettsial organisms |