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Pharm-Cephalosporins
Cephalosporins
| Question | Answer |
|---|---|
| Cephalosporin Clinical uses: | Cystitis, skin infections, pyoderma and soft tissue infections; mastitis, shipping fever and pneumonia in LA |
| Cephalosporin 2 important advantages over penicillin: | Active agains penicillinase producing bacteria, effective against some gram - bacteria as well as gram positive (Broad Spectrum) |
| Cephalosporin -static or -cidal | Bactericidal |
| Cephalosporin Spectrum of Activity | Broad |
| Cephalosporin Toxicity | Non-toxic |
| Cephalosporin Penicillinase Resistance | Resistant - Effective against all staph |
| Cephalosporin Cephalosporinase Resistance | Suseptible |
| Cephalosporin Excretion | Kidneys |
| Cephalosporin Metabolism | Liver |
| Cephalosporin Examples: | Simplicef, Convenia, Cefazolin/Ancef/Kefzol, Excenel, Naxcel, Cefa-Drops, Cefa-Tabs, Cefa-Lak. |
| What Cephalosporin form is used intramammary? | Cefa-Lak |
| What Cephalosporin form is available only for dogs? | Simplicef |
| Which Cephalosporin form must be given slowly? (Can cause nausea, seixuring and vomiting if too fast.) | Cefazolin |
| Which Cephalosporin form is effective for 14 days? | Convenia |
| Which Cephalosporin form is approved for lactating dairy animals? | Naxcel |
| Other Cephalosporin dosage forms | Cefaclor/Ceclor, Cefepime/Maxipime, Cefotaxime/claforan, Cefotaxime/Claforan, Cefotetan/Cefotan, Cefoxitin/Mefoxin, Ceftazidime, Cephalothin, Cephradine, Cefpodoxime |
| Cephalosporin Side Effects | Allergic reactions, rare bleeding disorders, seizures, v/d |