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Pharm-Penicillins
Penicillin
| Question | Answer |
|---|---|
| Penicillin -static vs. -cidal | Bactericidal |
| Penicillin Toxicity | Low |
| Penicillin Allergic Reactions | Possible |
| Penicillin Spectrum of Activity | Some are broad, some are narrow |
| Penicillin Stability | Varied |
| Penicillin Excretion | Renal (some liver) |
| Enzyme produced by some bacteria that inactivates penicillin? | Penicillinase |
| Penicillinase commonly produced by ________. | Staphylococcus |
| Result of the first modification to penicillin was _______. | Penicillin V |
| What is the additive that inactivates penicillinase? | Clavulanate potassium |
| What makes up Clavamox? | Amoxicillin + Clavulanate potassium |
| Is penicillin excreted in its active form? | Yes, when excreted from the liver |
| Dosage forms of penicillin: | Amoxicillin, Ampicillin, Penicillin V, Clavamox, Carbenicillin, Cloxacillin, Dicloxacillin, Penicillin G & Ticarcillin. |
| Clavamox used to treat: | Pneumonia, Bronchitis, UTIs and skin infections |
| Clavamox handling: | Protect from oxygen and light! Packaged in airtight foil packets |
| Broad or Narrow: Ampicillin | Broad |
| Broad or Narrow: Amoxicillin | Broad |
| Broad or Narrow: Clavamox | Broad |
| Broad or Narrow: Penicillin V/G | Narrow |
| Penicillin Side effects | v/d, nausea, allergic reactions, GI upset |