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Piperacillin/Tazobactam Zosyn (IV)
Ticarcillin/Clavulanic Acid Timentin (IV)
Cefazolin Ancef (IV)
Cephalexin Keflex (PO)
Cefaclor Ceclor
Cefuroxime Ceftin
Ceftriaxone Rocephin; no neonates/ peds--> bilirubin buildup. Dont take with Calcium
Ceftazidime Fortaz *pseudomonal
Cefepime Maxipime *pseudomonal
Ceftaroline Teflaro # anti-MRSA
Ertapenem Invanz; longest half life, Q24, good for outpatient
Imipenem/Cilastatin Primaxin
Meropenem Merrem
Doripenem Doribax
Aztreonam Azactam
PO penicillins 12,459
IV penicillins 4 is IV and PO, everything else besides 12,459 up to 11
Type 1 IgE; anaphylaxis
Type 2 IgG, IgM
Type 3 Antigen- Antibody
Type 4 Not known T-lymphocytes
PCN drug interactions tetracycline (antagonism), warfarin, aminoglycosides (same IV bag), and probenecid (prevents PCN elimination)
DON NOT RENAL, positive only
B-lactamase inhibitors clavulanic acid, sulbactam, tazobactam
Cefoxitin Mefoxin, is a cephamycin
Cefotetan Cefotan, is a cephamycin
Carbapenem "penems" ADR's and DI's seizure and valproic acid; 5-10% cross allergic potential
What helps Imipenem from being broken down in renal tubule? Cilastatin
Which Carbapenem isnt anti-pseudomonal? Ertapenem
What do we give patients allergic to PNC? Monobactam; Aztreonam (Azactam); gram negative and anti-pseudomonal
Polyenes Ampho B (systemic) and Nystatin (not systemic)
Bind ergosterol--> pores that let in ions--> cell death Polyenes (Ampho B and Nystatin)
Inhibits 14a- sterol demthylase--> no conversion lanosterol to ergosterol --> low ergosterol--> disrupted cell membrane Azoles (Imidazoles and Triazoles)
Inhibit conversion of aqualene-->lanosterol--> squalene buildup (toxic) allylamines/ benzylamines
Inhibits synthesis of B-1,3 glycan--> disrupts cell wall--> lysis --> death Echinocandins (C.A.M-fungins)
Inhibits mitosis, may also inhibit RNA and DNA synthesis Griseofulvin
Anti-fungal that inhibits DNA synthesis by messing with thymidylate synthase; converts to 5FU Antimetabolites (Flucytosine)
Antifungal that inhibits transport of elements Ciclopiroz (Tolnaftate)
Created by: angieryx