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VT 2100 The Rat
Lab Rat Needs
Question | Answer |
---|---|
Order? | Rodentia |
Define Murine | Refers to mice & rats |
2 common species of Rats | Rattus Rattus Rattus norvegicus |
Common name of Rattus Rattus | Black Rat |
Common name Rattus Norvegicus | Brown or Norway Rat |
Majority of Lab rats are a Variety of this species.... | Rattus Norvegicus |
Life span | 26-40 months |
Weight | 267-500g (M) 225-325 (F) |
Tail constitutes __% of body length | 85% |
Tail Functions | Balance and Heat Loss |
The lacrimal gland is called | Harderian Gland |
The Harderian gland secretes | porphyrin |
Term for porhyrin secretions in ill or stressed rats | Chromodacryorrhea |
define hypsodontic | teeth that continuously grow |
Which lung is smaller and singular lobed | Left |
What are the four sections of the right lung lobe? | Cranial, middle, accessory, caudal |
Define Hibernation Tissue | Brown fat |
Hibernation Tissue provides __x the energy storage | 10x |
Where is hibernation tissue found? | around the neck in between the scapulas |
How many pairs of anterior vena cavas? | 2 |
Rats have what type of stomachs? | Monogastric |
The stomach is divided into ______ and ______ | glandular and nonglandular forestomach |
define the limiting ridge | structure that separates the two sections of the stomach and covers the esophagus opening |
What is responsible for the inability to vomit? | The limiting ridge |
Define Hindgut fermenter | in small intestine contains cecum similar to rumen |
Females have ___-___ pairs of mammary glands | 4-6 |
Where are the mammary glands located? | the thoracic and inguinal regions |
they have a _____ uterus | Bicornate |
list research involved wit rats | Diabetes cataracts obesity immunology |
Females are continuously in what stage of reproduction? | Polyesteous |
How many estrous periods do they have? | 4-5 day |
Postpartum estrous occurs when? | 20-24 hrs after parturition |
When does weaning occur? | 3-4weeks |
Puberty occurs when for females | 37-67 days |
Puberty occurs when for males? | 40-75 days |
Length of gestation | 21-23 Days |
Litter size | 6-13 pups |
Pups develop hair in | 7-10days |
Pups ears open in | 3-5 days |
Pups eyes open in | 7-14days |
Pups eat solid food by the | end of second week |
Vaginal plug made of | dried semen and vaginal secretions |
how long does the vaginal plug last for? | 24 hours |
What can the presence of a vaginal plug tell us? | confirms breeding |
Define monogamous | 1 Female and 1 Male |
define Polygamous | 1 male and 2+ Females |
define Intensive reproduction | continuous housing of male and female |
define Non-intensive reproduction | separate housing of male and females |
Define Stock | randomly bred |
define outbred | randomly bred |
common outbred stocks are | Sprague-Dawley (SD) Long-Evans (LE) Winstar (WI) |
When describing a stock what is used to separate the description and source | a colon |
define strain | inbred |
define inbred | at least 20 generations of bro sis or parent offspring |
Goal of inbreeding | to develop a strain that are genetically homozygous |
Common inbred strains are | Albany (ALB) Buffalo (BUF) |
Strain is designated in..... | Upper case |
A substrain follows a | slant line |
Define Coisogenic | strain the develops from genetic mutation |
define congenic | mutations transferred to another strain threw backcross mating |
define hybrid | mating between two different inbred strains |
define transgenic | removing DNA and inserting it into a ovum after fertilization |
a group of rats is called a | Mischief |
housing temp | 65-75 degrees |
housing Humidity | 40-60% |
cause of ring tail is | low humidity |
Normal water consumption | 22-33ml/day |
normal food consumption | 15-20g/day |
pregnant or lactating require ___x more food | 4x |
grabbing a rat by the tail causes a _____ injury | degloving |
Restraint devices | boxes or cones |
permanent ID systems | tattooing, ear punch/tag, microchpping |
IV injections sites | Saphenous Jugular Femoral or latteral tail vein |
most commonly used IV injection site | Lateral tail vein |
_____ and _____ helps vessel visualization | Heat and vasodialtion oils |
Which IV injections require anesthesia | saphenous, jugular, and femoral |
SQ injection needle gauge | 21g or smaller |
SQ injection site | scruff |
IM injection site | quadriceps, gluteals, and triceps |
IM injection needle gauge | 22g or smaller |
IP injection site | spine in abdominal wall |
define oral Gauge | feeding needle into esophagus for meds |
how do you determine depth of anesthesia | toe pinch reflex |
major concern with general anesthesia | hypothermia |
total blood volume in rats | 50ml/kg |
no more than ___% of blood can be taken | 10 |
Small amounts of blood can be taken from | tail/toenail clip |
large amounts of blood can be taken from | tail veins |
general anesthesia requires blood collection from | retoorbital plexus jugular femoral |
what type of tube is used for large amount of blood | EDTA |
what type of tube is used for small amounts of blood | heparinized capillary tubes |
caustive agent for murine respiratory mycoplasmosis | mycoplasma pulmonis |
what helps control myco? | oxytetracycline in water |
Common chronic bacterial infection | murine respiratory mycoplasmosis |
disease reported in all lab animals | Tyzzer's disease |
Caustive agent for tyzzer's disease | bacillus piliformis |
Tyzzer's disease confirmed by | ELISA testing |
Tyzzer's is transmitted by | gecal oral route |
Clinical signs of Tyzzer's disease | anorexia and diarrhea |
grey foci found on | liver, spleen, heart |
Treatment of Tyzzer's disease | Tetracycline |
Healthy rats harbor/carry what bacteria in the URT? | Pasterurellosis |
Pasteurellosis clinical signs | UR infection abscesses |
Treatment of Pasterurellosis | oxytetracuclin |
What is found in the nasopharynx of healthy rats | streptovacillosis |
Rat bite fever or hay fever also known as | streptobacillosis |
Caustive agent of streptobacllosis | streptobacillus moniliformis |
what disease can be transmited to humans from rat bites | streptobacillosis (ratbite/hay fever) |
Signs of Sialodacryoadenitis | swollen salivary harderian glands cornea dessication |
Most signification viral disease in rats | sialodacryoadenitis |
What is subclinical in rats but can kill mouses | sendia virus |
Aka Ringworm | Trichophyton mentagrophytes |
Common Nematodes | Aspicularis Tetraptera Syphacia |
Moniliformis | Thorny headed worm |
Moniliformis | |
The dwarf tape worm | Hymenolepis nana |
Which parasite is zoonotic | Hymenolepis nana |
Exceptable methods of euthanasia | Barbiturate overdose Co2 chamber Decapitation Exsanguination |
What can be used in euthanasia if sedation cannot | Dip in liquid nitrogen |
Husbandry related diseases | Fighting trauma Barbering Ringtail malocclusion |