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VT 2100 The Rat
Lab Rat Needs
| Question | Answer |
|---|---|
| Order? | Rodentia |
| Define Murine | Refers to mice & rats |
| 2 common species of Rats | Rattus Rattus Rattus norvegicus |
| Common name of Rattus Rattus | Black Rat |
| Common name Rattus Norvegicus | Brown or Norway Rat |
| Majority of Lab rats are a Variety of this species.... | Rattus Norvegicus |
| Life span | 26-40 months |
| Weight | 267-500g (M) 225-325 (F) |
| Tail constitutes __% of body length | 85% |
| Tail Functions | Balance and Heat Loss |
| The lacrimal gland is called | Harderian Gland |
| The Harderian gland secretes | porphyrin |
| Term for porhyrin secretions in ill or stressed rats | Chromodacryorrhea |
| define hypsodontic | teeth that continuously grow |
| Which lung is smaller and singular lobed | Left |
| What are the four sections of the right lung lobe? | Cranial, middle, accessory, caudal |
| Define Hibernation Tissue | Brown fat |
| Hibernation Tissue provides __x the energy storage | 10x |
| Where is hibernation tissue found? | around the neck in between the scapulas |
| How many pairs of anterior vena cavas? | 2 |
| Rats have what type of stomachs? | Monogastric |
| The stomach is divided into ______ and ______ | glandular and nonglandular forestomach |
| define the limiting ridge | structure that separates the two sections of the stomach and covers the esophagus opening |
| What is responsible for the inability to vomit? | The limiting ridge |
| Define Hindgut fermenter | in small intestine contains cecum similar to rumen |
| Females have ___-___ pairs of mammary glands | 4-6 |
| Where are the mammary glands located? | the thoracic and inguinal regions |
| they have a _____ uterus | Bicornate |
| list research involved wit rats | Diabetes cataracts obesity immunology |
| Females are continuously in what stage of reproduction? | Polyesteous |
| How many estrous periods do they have? | 4-5 day |
| Postpartum estrous occurs when? | 20-24 hrs after parturition |
| When does weaning occur? | 3-4weeks |
| Puberty occurs when for females | 37-67 days |
| Puberty occurs when for males? | 40-75 days |
| Length of gestation | 21-23 Days |
| Litter size | 6-13 pups |
| Pups develop hair in | 7-10days |
| Pups ears open in | 3-5 days |
| Pups eyes open in | 7-14days |
| Pups eat solid food by the | end of second week |
| Vaginal plug made of | dried semen and vaginal secretions |
| how long does the vaginal plug last for? | 24 hours |
| What can the presence of a vaginal plug tell us? | confirms breeding |
| Define monogamous | 1 Female and 1 Male |
| define Polygamous | 1 male and 2+ Females |
| define Intensive reproduction | continuous housing of male and female |
| define Non-intensive reproduction | separate housing of male and females |
| Define Stock | randomly bred |
| define outbred | randomly bred |
| common outbred stocks are | Sprague-Dawley (SD) Long-Evans (LE) Winstar (WI) |
| When describing a stock what is used to separate the description and source | a colon |
| define strain | inbred |
| define inbred | at least 20 generations of bro sis or parent offspring |
| Goal of inbreeding | to develop a strain that are genetically homozygous |
| Common inbred strains are | Albany (ALB) Buffalo (BUF) |
| Strain is designated in..... | Upper case |
| A substrain follows a | slant line |
| Define Coisogenic | strain the develops from genetic mutation |
| define congenic | mutations transferred to another strain threw backcross mating |
| define hybrid | mating between two different inbred strains |
| define transgenic | removing DNA and inserting it into a ovum after fertilization |
| a group of rats is called a | Mischief |
| housing temp | 65-75 degrees |
| housing Humidity | 40-60% |
| cause of ring tail is | low humidity |
| Normal water consumption | 22-33ml/day |
| normal food consumption | 15-20g/day |
| pregnant or lactating require ___x more food | 4x |
| grabbing a rat by the tail causes a _____ injury | degloving |
| Restraint devices | boxes or cones |
| permanent ID systems | tattooing, ear punch/tag, microchpping |
| IV injections sites | Saphenous Jugular Femoral or latteral tail vein |
| most commonly used IV injection site | Lateral tail vein |
| _____ and _____ helps vessel visualization | Heat and vasodialtion oils |
| Which IV injections require anesthesia | saphenous, jugular, and femoral |
| SQ injection needle gauge | 21g or smaller |
| SQ injection site | scruff |
| IM injection site | quadriceps, gluteals, and triceps |
| IM injection needle gauge | 22g or smaller |
| IP injection site | spine in abdominal wall |
| define oral Gauge | feeding needle into esophagus for meds |
| how do you determine depth of anesthesia | toe pinch reflex |
| major concern with general anesthesia | hypothermia |
| total blood volume in rats | 50ml/kg |
| no more than ___% of blood can be taken | 10 |
| Small amounts of blood can be taken from | tail/toenail clip |
| large amounts of blood can be taken from | tail veins |
| general anesthesia requires blood collection from | retoorbital plexus jugular femoral |
| what type of tube is used for large amount of blood | EDTA |
| what type of tube is used for small amounts of blood | heparinized capillary tubes |
| caustive agent for murine respiratory mycoplasmosis | mycoplasma pulmonis |
| what helps control myco? | oxytetracycline in water |
| Common chronic bacterial infection | murine respiratory mycoplasmosis |
| disease reported in all lab animals | Tyzzer's disease |
| Caustive agent for tyzzer's disease | bacillus piliformis |
| Tyzzer's disease confirmed by | ELISA testing |
| Tyzzer's is transmitted by | gecal oral route |
| Clinical signs of Tyzzer's disease | anorexia and diarrhea |
| grey foci found on | liver, spleen, heart |
| Treatment of Tyzzer's disease | Tetracycline |
| Healthy rats harbor/carry what bacteria in the URT? | Pasterurellosis |
| Pasteurellosis clinical signs | UR infection abscesses |
| Treatment of Pasterurellosis | oxytetracuclin |
| What is found in the nasopharynx of healthy rats | streptovacillosis |
| Rat bite fever or hay fever also known as | streptobacillosis |
| Caustive agent of streptobacllosis | streptobacillus moniliformis |
| what disease can be transmited to humans from rat bites | streptobacillosis (ratbite/hay fever) |
| Signs of Sialodacryoadenitis | swollen salivary harderian glands cornea dessication |
| Most signification viral disease in rats | sialodacryoadenitis |
| What is subclinical in rats but can kill mouses | sendia virus |
| Aka Ringworm | Trichophyton mentagrophytes |
| Common Nematodes | Aspicularis Tetraptera Syphacia |
| Moniliformis | Thorny headed worm |
| Moniliformis | |
| The dwarf tape worm | Hymenolepis nana |
| Which parasite is zoonotic | Hymenolepis nana |
| Exceptable methods of euthanasia | Barbiturate overdose Co2 chamber Decapitation Exsanguination |
| What can be used in euthanasia if sedation cannot | Dip in liquid nitrogen |
| Husbandry related diseases | Fighting trauma Barbering Ringtail malocclusion |