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VT2100 The Mouse

Housing, Disease, basics of Lab Mice

Name of laboratory mouse Mus Musculus
AKA name of Lab mouse Swiss albino or house mouse
Live span 12-36months
Weight of male 20-40G
Weight of Female 22-63g
Forelimbs have __# of digits 4
Hindlimbs have __# of digits 5
What is special about their bone marrow? remains active in long bone for lifetime
Orbital plexus to rats is as __________ is to mice orbital sinus
Incisors are ______ and ______ open rooted, hypsodont
Which cartlage is fused? costochondral
Esophagus lacks mucous glands
Estrus cycle 4-5 days
Gestation length 19-21days
Puberty at 6 weeks
Weaning at 3 weeks
Postpartum estrus occurs 14-28 hours after partuition
must leave newborns alone for ___ days 2
Ears open at 3days
Eyes open at 12-14days
Hair grows in at 7 days
Females are bred until 9month old
Several females housed together will go into.... anestrus period
define whitten Effect several females exposed to male odor
length of time of whitten effect 3 days
what stage does the whittening effect lead to estrus
define bruce effect prego female exposed to new male odor
length of time of bruce effect within 4 days
What does the bruce effect lead to? abortion
TNZ 65-85 degrees
Relative Humididty 40-60%
define coprophagia eating pp is normal for mice
water consumption 5-8ml/day
Define temporary ID nontoxic marker on tail or coat
define permanet ID ear punch/tag microchip
IV injection site Lateral tial vien
IP injection site lower right quadrant of abdomen
IM injection site quadriceps in hind leg
SQ injection site scruff
oral gavage needle size 20g x 1.5 needle
rotating tip during oral gavage causes rupture of esophagus
Perfered site of blood collection retroorbital sinus
blood collection sites (4) toe/tail ckip cardiocentesis retroorbital sinus tail vein
anesthesia required for all blood collection except (2) tail or toe clip
what blood colection is terminal cardiocentesis
Causative agent for pneumonia mycoplasma plumonis
what causes hepatic tumors and hepatitis helicobacter
primary cause of repiratory disease sendia virus
nearly 100% wild mice have lymphocytic choriomenigitis
Zoonotic disease Lymphocytic choriomenigitis
Lymphocytic choriomenigitis is transmitted by (4) AEROSOL, BITES, TRASPLACENTALLY, TICKS
most common nematodes (2) Aspicularis tetraptera syphacia obvelata
Fur mites (2) Myobia Musculi Mycoptes musclinus
Outbred mice noninfectious disease pulmonary tumors
inbred mice noninfectious disease oncogenic viruses
Murine oncogenic viruses transmitted by (2) placental transfer transmammary (suckling)
Created by: LittleLette