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VetMed SAMS4

GI Pharmacology

Targets of Most Anti-Emetic Rx serotonin dopamine NK-1 (substance P)
Motion Sickness H1 antihistamines - dimenhydronate, meclizine anticholinergics
Central Antidopaminergic Anti-Emetic Rx metaclopramide (Reglan) - C/I in horses phenothiazine tranqs - C/I if hypotensive, hypothermic
Serotonin 5-HT3 Receptor Antagonist Anti-Emetic Rx ondansetron dolasetron blocks cisplatin-induced emesis
NK-1 Receptor Antagonist Anti-Emetic Rx Cerenia
Antacid Rx NaHCO3 AlOH CaOH + MgOH
H2 Blocker Ulcer Rx cimetidine (Tagamet) ranitidine (Zantac) famotidine (Pepcid) Nizatidine (Axid)
Proton Pump Inhibitor Rx omeprazole (Prilosec, Gastrogard)
Reestablishing Cytoprotective Mucus Rx misoprostol (Cytotec)
"Bandaging" the Ulcer Rx sucralfate (Carafate)
Tx for NSAID-Induced Gastric Ulcer 1 - misoprostol 2 - omeprazole 3 - H2 blockers
Tx for Steroid-Induced Gastric Ulcer 1 - H2 blockers 2 - omeprazole 3 - misoprostol
Tx for Intestinal/Colonic Ulcer sucralfate
Created by: 26509889