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VetMed SAMS4
GI Pharmacology
Question | Answer |
---|---|
Targets of Most Anti-Emetic Rx | serotonin dopamine NK-1 (substance P) |
Motion Sickness | H1 antihistamines - dimenhydronate, meclizine anticholinergics |
Central Antidopaminergic Anti-Emetic Rx | metaclopramide (Reglan) - C/I in horses phenothiazine tranqs - C/I if hypotensive, hypothermic |
Serotonin 5-HT3 Receptor Antagonist Anti-Emetic Rx | ondansetron dolasetron blocks cisplatin-induced emesis |
NK-1 Receptor Antagonist Anti-Emetic Rx | Cerenia |
Antacid Rx | NaHCO3 AlOH CaOH + MgOH |
H2 Blocker Ulcer Rx | cimetidine (Tagamet) ranitidine (Zantac) famotidine (Pepcid) Nizatidine (Axid) |
Proton Pump Inhibitor Rx | omeprazole (Prilosec, Gastrogard) |
Reestablishing Cytoprotective Mucus Rx | misoprostol (Cytotec) |
"Bandaging" the Ulcer Rx | sucralfate (Carafate) |
Tx for NSAID-Induced Gastric Ulcer | 1 - misoprostol 2 - omeprazole 3 - H2 blockers |
Tx for Steroid-Induced Gastric Ulcer | 1 - H2 blockers 2 - omeprazole 3 - misoprostol |
Tx for Intestinal/Colonic Ulcer | sucralfate |