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VetMed SAMS1
Respiratory Pharmacology
Question | Answer |
---|---|
Topical Anesthetic for Sneezing | provaricane lidocaine + bicarbonate |
Peripherally Acting Cough Suppressants | mucosal anesthetics (cough drops) demulcents (syrups) bronchodilators |
Centrally Acting Cough Suppressants | antihistamines - diphenhydramine, benadryl non-narcotic antitussives - dextromethorphan narcotic antitussives - codeine, hydrocodone narcotic agonist/antagonist - butorphanol |
Leukotriene Inhibitors for Inflammation | zafirlukast - Accolate montelukast - Singulair tepoxalin - Zubrin |
Decrease Pulmonary Capillary Pressure | morphine (decreases preload) furosemide (decreases preload & produces local PG in lung) (methylxanthines) |
Decrease Severe Pulmonary Hypertension | oxygen sildenafil (Viagra) (prostacyclin, bosentan (Tracleer), calcium channel blockers) |
Mixed Adrenergic Agonist for Bronchodilation | epinephrine |
Mixed Beta Adrenergic Agonist for Bronchodilation | isoproterenol |
Beta-2 Adrenergic Agonist for Bronchodilation | terbutaline albuterol metaproterenol clenbuterol metaproterenol |
Methylxanthines | bronchodilation (not as good as beta-2) theophylline (aminophylline is IV form) |
Decreases Half-Life of Theophylline | phenobarbitol |
Increases Half-Life of Theophylline | fluoroquinolones cimetidine erythromycin propranolol |
Anti-cholindergic Drugs | bronchodilation too many side effects to routinely used |
Stimulates Tubulo-Acinar Glands | saline expectorants or glyceryl guaiacolate (human) volatile oils NOT cholinergics |
Chemically Cleaves Mucus Disulfide Bonds | nebulized acetyl cysteine |
Increase Surfactant Production | dexamethasone, betamethasone to dam >36hrs before birth exogenous surfactants intubated into neonate otherwise |
Control Respiratory Rate and Character | analeptic agents - doxapram narcotics - morphine |
May Cause Bronchospasm Side Effect | cholinergics, anticholinesterase propranolol, aspirin |
May Dry Out Respiratory Trct | anticholinergics antihistamines |
May Cause Pulmonary Edema | cisplatin splats cats fluids overload |
May Cause Pneumonitis | bromide overdose |