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Cholinergic Agents
Cholinergic Agents (Parasympathomimetic)
| Term | Definition |
|---|---|
| Acetylcholine | direct-acting cholinergic that is seldom used clinically because it is broken down so rapidly by acetylcholinesterase |
| Carbamylcholine | direct-acting cholinergic that is used to treat atony of the GI tract and to stimulate uterine contractions in swine. |
| Bethanechol | direct-acting cholinergic that is used to treat GI and urinary tract atony |
| Pilocarpine (Isopto Carpine) | direct-acting cholinergic that reduces intraocular pressure associated with glaucoma and is used to treat keratoconjunctivitis sicca |
| Metoclopramide (Reglan) | direct-acting cholinergic that is used to control vomiting and to promote gastric tract emptying |
| Edrophonium | indirect-acting cholinergic (anticholinesterase) that is primarily used in the presumptive diagnosis of myasthenia gravis |
| Neostigmine (Prostigmine) | indirect-acting cholinergic (anticholinesterase) are used to treat urine retention and GI atony and are used as an antidote to neuromuscular blocking agents |
| Physostigmine (Antilirium) | indirect-acting cholinergic (anticholinesterase) uses of this product are similar to those of neostigmine |
| Organophosphate compounds | indirect-acting cholinergic (anticholinesterase) used as insecticide dips and may result in toxicity if used inappropriately |
| Demecarium (Humorsol) | indirect-acting cholinergic (anticholinesterase) used in the preventive management of glaucoma |
| Pyridostigmine (Mestinon) | indirect-acting cholinergic (anticholinesterase) used for the treatment of myasthenia gravis |
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