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PHARMACOLOGY PART 1
General Pharmacology, Drug Administration, and Calculations
| Question | Answer |
|---|---|
| Pharmacokinetics | “What the body does to the drug”- Absorption, Distribution, Metabolism (Biotransformation), Excretion |
| Pharmacodynamics | “What the drug does to the body”-Receptors, Types of Drug Actions, Dose–Response, Potency vs. Efficacy, Therapeutic Index (TI), Adverse Effects |
| Barriers | BBB, placenta. |
| Therapeutic Index (TI) | TI = LD₅₀ / ED₅₀. Higher TI = safer drug. Low TI = narrow margin of safety (e.g., chemo drugs) |