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Cushing's & Addisons
Unit 4 Section 4
| Question | Answer |
|---|---|
| What is cushing's disease? | Hyperadrenocorticism |
| What is Addison's disease? | Hypoadrenocorticism |
| Which one is most common in young to middle aged female dogs? | Hypoadrenocorticism / Addison's disease |
| What causes Cushing's disease? | Chronic overproduction of cortisol |
| What are the 3 types of Cushing's? | - Pituitary dependant - Adrenal dependant - Latrogenic Cushing's |
| What percentage of adrenal functions is compromised before clinical signs of Addison's appear? | 90% |
| What are 3 clinical signs of Addison's? | - anorexia - lethargy - V+ / D+ |
| Which type of Cushing's is most common and by what percentage? | Pituitary dependant, 80% of cases |
| What are signs of an Addison's crisis? | - ataxia, weakness, shaking, non responsive - bradycardic |
| How is Addison's diagnosed? | - blood tests - ACTH stimulation tests - ECG |
| How is Cushing's diagnosed? | - blood tests - abdo x-ray / ultrasound - ACTH stimulation test - Dex suppression test |
| What are some treatment options for Cushing's | - Trilostane - Mitotane - Adrenalectomy - Radiation therapy |