Save
Busy. Please wait.
Log in with Clever
or
show password
Forgot Password?
Don't have an account?  Sign up 
Sign up using Clever
or
Username is available taken
show password


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account. Your email address is only used to allow you to reset your password. See our Privacy Policy and Terms of Service.

Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
focusNode
Didn't know it?
click below
 
Knew it?
click below
Don't Know
Remaining cards (0)
Know
0:00
edit
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

Clin Path Quiz 10/11

Lecture 10: Clinical Chemistry

QuestionAnswer
clinical chemistries evaluation of chemical components of the blood; most tests are specific markers for problems in specific organs or body systems, measurements aid in diagnosis, treatment, and monitoring
chemical components dissolved substances normally found in the blood, substances carried by the blood to specific organs, substances not normally found in the blood
2 main categories of chemical components physiologic function and enzymes
sample collection for clinical chemistry same as CBC venipuncture procedure
what samples can be utilized in blood chemistry tests? serum, heparinized plasma, heparinized WBCs, urine
blood collection tubes used for clinical chemistry red top tube (serum), tiger top/camo tubes (serum), green top tubes (heparinized plasma/whole blood)
red top tubes used for serum collection, NO anticoagulant
tiger top or camo tubes used for serum collection, clot separator gel to physically separate serum from the clot
green top tubes heparinized plasma or whole blood samples
how do you prepare a serum sample? collect the blood and place in a tube without anticoagulant, allow blood to clot at room temperature for 15-30 minutes, centrifuge sample at 2000 rpms for 10 minutes to separate clot, carefully pipette the serum off the top, why transfer a clean container
why do you not allow the sample to sit when preparing a plasma sample? the plasma is not supposed to clot
inaccurate results can be caused by inappropriate anticoagulant use, delayed separation of serum/plasma from clot, plasma, serum sample discoloration, hemolysis, linearity
biggest example of inappropriate anticoagulant usage of EDTA tubes
EDTA will lead to a falsely decreased calcium and magnesium, increased potassium
always avoid ______ for chemistry testing EDTA
delayed separation will increase phosphorous and potassium and decrease blood glucose
plasma/serum discoloration interferes with the light measurement used to detect enzyme activity; lipemia is the most likely coloration to interfere
solutions for lipemia ultra-high speed centrifugation, refrigerate serum/plasmas (lipids will float to the top), fast animal overnight and recollect sample (only effective is lipemia is post-prandial)
hemolysis in vitro or due to traumatic sample collection; RBCs contain enzymes as well at magnesium, phosphorous, potassium, all will be released into the blood causing false elevations
linearity when results are above the max set value on analyzer; will show as too high to read or > (max set value)
solution to linearity following instructions to further dilute the sample, which will be based on the machine
physiologic functions measured at concentrations (mg/dL)
enzymes INDICATE TISSUE INJURY; measured as activity, IU/L (international units per liter)
enzymology organ tissues contain enzymes that assist in their normal function, these enzymes increase in serum or plasma following tissue injury to that organ; some enzymes are organ-specific, some are non-specific
isoenzymes subfractions of enzymes that may be organ specific
causes of INCREASED enzymes leakage from affected cells, induction of enzyme synthesis by affected cell, decrease in activation, clearance, or excretion of enzyme, absorption of maternal enzymes from colostrum ingestion in neonates
rule out test high sensitivity, enzyme activity should increase following the selected disease occurrence, high incidence of TRUE POSITIVE results, few false negatives; SNOUT
rule in test high specificity, enzyme activity should REMAIN LOW if the disease is not present, high incidence of TRUE NEGATIVE results, few false positives; SPIN
Created by: mkroon26
Popular Veterinary sets

 

 



Voices

Use these flashcards to help memorize information. Look at the large card and try to recall what is on the other side. Then click the card to flip it. If you knew the answer, click the green Know box. Otherwise, click the red Don't know box.

When you've placed seven or more cards in the Don't know box, click "retry" to try those cards again.

If you've accidentally put the card in the wrong box, just click on the card to take it out of the box.

You can also use your keyboard to move the cards as follows:

If you are logged in to your account, this website will remember which cards you know and don't know so that they are in the same box the next time you log in.

When you need a break, try one of the other activities listed below the flashcards like Matching, Snowman, or Hungry Bug. Although it may feel like you're playing a game, your brain is still making more connections with the information to help you out.

To see how well you know the information, try the Quiz or Test activity.

Pass complete!
"Know" box contains:
Time elapsed:
Retries:
restart all cards