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immunology/serology

clin lab 3

QuestionAnswer
What are the two major internal defense systems INNATE, ADAPTIVE
what is innate also called non-specific immune system
what is the adaptive also called specific immune system and acquired immunity
what does the innate system fight against bacteria, viruses, fungus
what are the barriers of the innate immune system skin,physical and chemical parts of the nasopharynx, gut, lungs, genitourinary
signs of inflammation include pain, heat, redness, swelling, and loss of function
in the blood they are called monocytes, but when they migrate to various tissues and organs, they become what? MACROPHAGES
What are natural killer cells (NK) lymphocytes found in the blood and peripheral lymphoid organs.
Interferons are what cytokines
Adaptive immune system is divided in to 2 parts what are they humoral immune system and cell-mediated immune system
The adaptive immune system has the ability to respond specifically to what foreign substances
what type of wbc are largely responsible for the adaptive immune system lymphocytes
what does APC stand for antigen presenting cells
B-lymphocytes mature in whatq bone marrow
t-lymphocytes mature in the what thymus
immunoglobulin molecules are also know as what antibodies
specialized T-Lymphocytes are called what Helper T-Cells
The humoral immune system can recognize how many different antigens billions
How many antibodies are there 5
list the antibodies IgM, IgG, IgE, IgA, IgD
This antibody is the first produced in response to an antigen, and compromises approx. 5% of circulation immunoglobulin. IgM
This antibody is the most abundant, compromises 75% of circulating immunoglobulin and remains in circulation the longest IgG
this antibody is present in very small amounts, functions in immediate hypersensitivity reactions IgE
This antibody compromises approx. 20% of circulating immunoglobulin, functions in mucosal immunity, protection of respiratory, intestinal, and urogenital tracts IgA
This antibody when present is very low abundance, funtion is B-lymphocyte surface antigen receptor in some species IgD
True or FalseA neutralization antibody reaction occurs when antibody binds directly with the antigen TRUE
Do anitbodies coat microbes YES
What are the 2 types of T-effector cells Helper T Cells/lymphocytes (CD4+) and Cytolytic/lymphocytes (CD8+)
Helper T cells are effected by which virus in humans HIV/AIDS
Animals immune system does not what to its own cells destroy
Does the immune system discriminate between self and non-self which results in immunologic tolerance YES
True or False SOme immune responses have an adverse effect on the host animal TRUE
How many types of hypersensitivity diseases 4
Which type of hypersensitivity dz causes and immediate hypersensitivity that occurs when chemical mediators from mast cells are released Type I
Which type is where the anitibodies are directied against the animal's own cells Type II
Which type is and Immune Complex Disease Type III
Which type is a T-cell Mediated disease Type IV
what is it called when animals become passively resistant to dz by receiving maternal antibodies in the colostrum or by recieving preformed antibodies by injection Passive Immunity
What is accomplished by injecting a suspension of microorganisms into an animal to elicit an antibody response, but not causing the dz Immunization
What does attenuated mean weaken
what does inactivated mean killed microorganisms
What is added to a vaccine to enhance the normal immune response adjuvant
Do killed vaccines require more or less adjuvant more adjuvant
The science of detection and measurement of antibodies or antigens is called what Serology
How many canine blood groups are there 12
How many feline blood groups are there 1
what is a feline blood group desingnated by the AB system (a,b,ab)
The majority of cats have what group A
When does group B in feline present itself in purebred cats
Few cats have what group type AB
How many blood groups are in cattle 11 A,B,C,F,J,L,M,R,S,T,and Z
Group B in cattle have how many different antigens 60
How many blood groups in sheep 7 A,B,C,D,M,R,and X
How many blood groups are in goats 5 A,B,C,M,and J
How many blood groups in horses that are identified in 8 major blood group systems 30 A,C,D,K,P,Q,T and U
Crossmatching should be done before the first transfusion because reactions are commonly what fatal
What type of blood sample do you need to do a major crossmatch serum and whole blood sample
What type of blood samples do you need to do a minor crossmatch serum and whole blood sample
Whole blood should not be used when what is specified on collecting samples for serologic testing serum or plasma
What color tube is used when serum is required and what color tube is used when plasma is required red serum and purple for plasma
Serum should be shipped warm or cold cold
Created by: scoobysnax