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ITAH - Pharmacology
Pharmacology
| Question | Answer |
|---|---|
| Define Pharmacology | The science of drugs, and especially of their actions in the body. |
| Define Clinical Pharmacology | The study of how drugs effect diseased patients. |
| Define Drug | A medicine or other substance which has a physiological effect when ingested or otherwise introduced to the body. |
| Define pharmacokinetics | The movement of drugs in the body, the effect of the body on the drug. |
| Define Pharmacodynamics | The effect of the drug on the body. |
| Define Pharmacotherapeutics | The study of the therapeutic uses and effects of drugs. |
| Define Toxicity | An adverse drug reaction or overdose. |
| What Is ADME (4 aspects) Of Pharmacokinetics? | Absorption Distribution Metabolism Excretion |
| What Factors Effect Drug Absorption? | -Drug form. -Tissue perfusion. -Physical/chemical properties. -Route of administration. |
| What Is Bioavailability? | How quickly after administration the active pharmaceutical agent becomes biologically available |
| What Factors Effect Drug Distribution? | -Natural barriers. -Walls of abscesses. -Placental. -Tissue perfusion. |
| Where Does Metabolism Of Drugs Occur? | -Lungs. -Liver. -kidneys. |
| What Factors Effect Drug Metabolism? | -Age. -Species. -Pre-disposing conditions. -Environment. -Nutritional status. |
| What Are The Two Main Routes Of Drug Excretion ? | -Urine via kidneys. -Faeces via liver. |
| What Are Some Examples Of Enteral Forms Of Medication? | -Tablets. -Capsules. -Powders. -Pastes. |
| What Is Parenteral Medication? | -Medication not by way of alimentary tract. -IV, SC, IM, topical etc. |
| What Are Some Examples Of Topical Medications? | -Ointments. -Sprays. -Creams. -Gels. -Drops. |
| What Are The Advantages/Disadvantages Of Oral Medication? | -Can be hidden in food. -Usually safe. -Palatable. -Sterility not an issue. -Dangers of reaction are low. -Slow onset of action. -Large dose required. -Inconsistency of absorption. -Poor technique can lead to harm (aggressive patient?). |
| What Are The Advantages/Disadvantages Of IV Medication? | -Rapid onset of action. -Rapid distribution. -Solutions that would irritate mucosa can be used via this route instead. -IV catheters for long term access. -Adverse reactions possible. -Short durations of action. -Must be a solution. -Stressful. |
| What Are The Advantages/Disadvantages Of IM Medication? | -Longer duration of action than IV. -Better for less cooperative patients. -Can use moderately irritant substances. -Duration of action is longer than SC. -Unpredictable rate of absorption. -Accidental IV can occur. -Stressful. |
| What Are The Advantages/Disadvantages Of SC Medication? | -Prolonged duration of action. -Can administer large volumes. -Quick and easy. -Less painful. -Unpredictable rate of absorption. -Local reactions may occur. -Avoid irritants. |