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ITAH - Pharmacology

Pharmacology

QuestionAnswer
Define Pharmacology The science of drugs, and especially of their actions in the body.
Define Clinical Pharmacology The study of how drugs effect diseased patients.
Define Drug A medicine or other substance which has a physiological effect when ingested or otherwise introduced to the body.
Define pharmacokinetics The movement of drugs in the body, the effect of the body on the drug.
Define Pharmacodynamics The effect of the drug on the body.
Define Pharmacotherapeutics The study of the therapeutic uses and effects of drugs.
Define Toxicity An adverse drug reaction or overdose.
What Is ADME (4 aspects) Of Pharmacokinetics? Absorption Distribution Metabolism Excretion
What Factors Effect Drug Absorption? -Drug form. -Tissue perfusion. -Physical/chemical properties. -Route of administration.
What Is Bioavailability? How quickly after administration the active pharmaceutical agent becomes biologically available
What Factors Effect Drug Distribution? -Natural barriers. -Walls of abscesses. -Placental. -Tissue perfusion.
Where Does Metabolism Of Drugs Occur? -Lungs. -Liver. -kidneys.
What Factors Effect Drug Metabolism? -Age. -Species. -Pre-disposing conditions. -Environment. -Nutritional status.
What Are The Two Main Routes Of Drug Excretion ? -Urine via kidneys. -Faeces via liver.
What Are Some Examples Of Enteral Forms Of Medication? -Tablets. -Capsules. -Powders. -Pastes.
What Is Parenteral Medication? -Medication not by way of alimentary tract. -IV, SC, IM, topical etc.
What Are Some Examples Of Topical Medications? -Ointments. -Sprays. -Creams. -Gels. -Drops.
What Are The Advantages/Disadvantages Of Oral Medication? -Can be hidden in food. -Usually safe. -Palatable. -Sterility not an issue. -Dangers of reaction are low. -Slow onset of action. -Large dose required. -Inconsistency of absorption. -Poor technique can lead to harm (aggressive patient?).
What Are The Advantages/Disadvantages Of IV Medication? -Rapid onset of action. -Rapid distribution. -Solutions that would irritate mucosa can be used via this route instead. -IV catheters for long term access. -Adverse reactions possible. -Short durations of action. -Must be a solution. -Stressful.
What Are The Advantages/Disadvantages Of IM Medication? -Longer duration of action than IV. -Better for less cooperative patients. -Can use moderately irritant substances. -Duration of action is longer than SC. -Unpredictable rate of absorption. -Accidental IV can occur. -Stressful.
What Are The Advantages/Disadvantages Of SC Medication? -Prolonged duration of action. -Can administer large volumes. -Quick and easy. -Less painful. -Unpredictable rate of absorption. -Local reactions may occur. -Avoid irritants.
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