Busy. Please wait.
or

show password
Forgot Password?

Don't have an account?  Sign up 
or

Username is available taken
show password

why


Make sure to remember your password. If you forget it there is no way for StudyStack to send you a reset link. You would need to create a new account.
We do not share your email address with others. It is only used to allow you to reset your password. For details read our Privacy Policy and Terms of Service.


Already a StudyStack user? Log In

Reset Password
Enter the associated with your account, and we'll email you a link to reset your password.
Don't know
Know
remaining cards
Save
0:01
To flip the current card, click it or press the Spacebar key.  To move the current card to one of the three colored boxes, click on the box.  You may also press the UP ARROW key to move the card to the "Know" box, the DOWN ARROW key to move the card to the "Don't know" box, or the RIGHT ARROW key to move the card to the Remaining box.  You may also click on the card displayed in any of the three boxes to bring that card back to the center.

Pass complete!

"Know" box contains:
Time elapsed:
Retries:
restart all cards
Embed Code - If you would like this activity on your web page, copy the script below and paste it into your web page.

  Normal Size     Small Size show me how

VTT 255 Test 3

Pharmacology drugs affecting the Nervous system

QuestionAnswer
What is the common used drugs for the Phenothiazines class Acepromazine, Chlorpromazine
What is the common used drugs for the Benzodiazepines class Diazepam (valium), Midazolam (versed)
What is the common used drugs for the Alpha-2 Agonists class Xylazine, Medetomidine, Detomidine
What is the common used drugs for the Barbituartes class Phenobarbital, Thiopental, Pentobarbital, Euthanasia containing Pedtobarbital
What is the effects of the Phenothiazines Penile prolapse in horse, no analgesia
What is the effects of the Benzodiazepines? no analgesia, generic diazepam given orally for several days has been kinled to liver failure
What is the effects of the Apha-2 agonists? Bradycardia, dogs may develop bloat which may require decompression, human precaution: will absorb through MM's and cuts
What is the effects of the Babiturates? Severe CNS depression, hypoproteinemic animals can have prolonged unconsciousness or death at normal doses
What is the contraindications/precautions of Phenothiazines? cautious-smaller doses should b given 2 animal w/liver dysfunc, cardiac dz, debilitation, & geriatrics; giant dogs, greyhnds may b extra senitive while terriers r somewhat resistant 2 its effects; boxers may b sensitive 2 the hypotensive, bradycardic effe
What is the contraindications/precautions of Benzodiazepines? IV slowly; caution in animals w/hepatic,renal dz,debilitated,geriatric,coma,shock; human brith defects n 1st tri;drugs cross the placents & n milk may cause CNS effects n neonates
What is the contraindications/precautions of Alpha-2 Agonists? Muscle temors, bradycardia, reduced RR, movement n response 2 loud noises, increased urination n cats, dogs may deelop bloat, horses will sweat, use w caution w other tranqs
What is the contraindications/precautions of Barbiturates? cate r extra sensitive 2 respiratory, Hpyoproteinemic animals can have prolonged unconsciousness or death @ normal doses, caution n acidotic animals
Is Phenothiazines a controlled substances? Is not a controlled substances
Is Benzodiazepines a controlled substances? Is a controlled substances
Is Alpha-2 Agonists a controlled substances? Is not a controlled substances
Is Barbiturates a controlled substances? Is a controlled substances
Does Phenothiazines lower the sezure threshold? Yes
Does Benzodiazepines lower the sezure threshold? No
Does ALpha-2 Agonists lower the sezure threshold? No
Does Barbiturates lower the sezure threshold? Yes
Does Phenothiazines have analgesic properies? No
Does Benzodiazepines have analgesic properies? No
Does Alpha-2 Agonists have analgesic properies? Yes
Does Barbiturates have analgesic properies? Yes
What is the common trade names for Diazepam? Valium
What is the common trade names for Midzaolam? Versed
What is the common trade names for Xylazine Rompun, AnaSed, Gemini
What is the common trade names for Medetomidine? Domitor
What is the common trade names for Detomidine? Dormosedan
What is the common trade names for Thiopental? Pentothal
What is the common trade names for Euthanasia Solutions contining Pentobarbital? Beauthanasia-D, FP-3, Sleepaway
What animals are effected by Phenothiazines and what happenes? Horses-penile prolapse
What animals are effected by Benzodiazepines and what happenes? Horses-muslce fasciculation, weakness, ataxiaCats-been linked to liver failure use only brand name ValiumDogs-may cause CNS excitement if used alone
What animals are effected by Alpha-2 Agonists and what happenes? Horses-stimulated w/loud noisedogs-may develop bloatCattle-w/Xylazine extra sensitive
What animals are effected by Barbiturates and what happenes? Cats-extra sensitive to the respiratory effects
What is the maximum injectable dose in dogs for Acepromazine? 3mg
What is the [ ] for Diazepam? 5mg/mL
What is the ratio with Ketamine and Diazepam? Equal volumes in the same syringe
What is the receral aganet for Benzediazepines? Flumazenil
What is the Routes of administration for Benzodiazepines? IV-Diazepam, Midazolam IM-Midzolam Oral-Diazepam
What is Zolazepam? In the Benzodiazepines class, a component of Telazol
What is the MOA for Alpha-2 Agonists? Stimulate alpha-2 receptors in the CNS causing a decrease in the level of norepinephrine; also the heart and blood vessels
What is the reversal agent for Xylazine? Yohimbine for dog and catTolazoline for horses
What is the reversal agent for Medetomidine? Atipamezole(Antisedan)
What is the reversal agent for Detomidine? Tolazoline
What is the reversal agent for Dexmedetomidine? Atipamezole (Antisedan)
What does the body do to Medetomidine? turns it into Dexmedetomindine
What is the MOA of Barbiturates? Depress the reticular activing center of the brian by inhibiting the release of ACH & norepinephrine; this results in less excitatory impules being able to pass into the cerebral cortex
What is the concept of redistribution? Drugs are made to attach themselves to lipophilic so they can cross the the wall of the blood/brain barrier
What is the classifications/times? long-acting 8-12 hrsshort-acting 45min - 2 hrsultra-short acting 5-30 min
What is the classifications/times of Phenobarbital? Long-acting
What is the classifications/times of Thiopental? ultra-short acting
What is the classifications/times of Pentobarbital? Short acting
What is the classifications/times of Euthanasia solutions? short acting
What is the 4 steps of the pain pathway? Transduction= stimulus of sensory nervesTransmission= the depolarization along the sensory nerve to spinal cord to brainModulation=transmission in spinal cord or brain by other neurotransmittersConscious perception= when brain is conscious aware
Why does pain perception change over time? pain receptors become more sensitve to stimulation over time
What is the wind up phenomenon? more nerve ending involved & the ones involved getting more insetive
Why is it important so know about the wind up? so we can make sure that the pt has pre op analgesics
What is NMDA? N-methyl-D-Aspartae receptors
What is the the MOA for Dissociatives? to reduce the CNS stimulation effects during indection or recovery
What is catalepsis? A condition that occurs in a variety of physical and psychological disorders and is characterized by lack of response to external stimuli and by muscular rigidity, so that the limbs remain in whatever position they are placed.
What are clinical signs of Dissociatives? lack of response to external stimuli and by muscular rigidity, so that the limbs remain in whatever position they are placed.
What is the [ ] for Ketamine? 100mg/ml
What is the ration of Ketamine w/ Diazepam? Equal volume of both in the same syringe
What is Tiletamine combined with? Zolazepam
Created by: Neonta