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Hematology ch.14
Tara's class
| Term | Definition |
|---|---|
| the ability of the body's systems to maintain the integrity of the blood and blood vessels | hemostasis |
| what does von Willebrand's factor do? | stabilize platelet plug |
| what initiates the mechanical phase of hemostasis | torn blood vessel |
| what attracts platelets to the torn part of the vessel | charge of the subendothelium |
| what triggers the chemical phase of hemostasis | adhesion and aggregation of platelets |
| platelets undergo what morphologic and physiologic changes during the mechanical phase | platelets adhere and expose PS on their outer membrane |
| chemical hemostasis involves | messengers |
| involves a number of factors intrinsic and extrinsic pathways results in a fibrin mesh or clot | coagulation cascade |
| what's the final phase of hemostasis | degradation of the fibrin clot |
| the formation of a stable platelet plug requires what 2 things | plenty of functional platelets and von Willebrand factor |
| membrane-bound cytoplasmic fragments are that are released from platelets, leukocytes, and endothelial cells that increase the surface area for a clot to form | microparticles |
| phosphatidylserine | PS |
| fibrinolysis produces what 2 substances | D-dimers, and FDPs |
| what triggers the conversion of fibrinogen to fibrin | thrombin |
| FDP | fibrin degradation products |
| tPA | tissue plasminogen activator |
| what factor binds to factor VIII (in the plasma to initiate coagulation | tissue factor (factor III) |
Created by:
MaryBI
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