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VET 111 Week 4
Ch 8 Endocrine Diseases
| Question | Answer |
|---|---|
| What does the endocrine system work with to maintain homeostasis? | Nervous system, Hypothalamus, and Pituitary gland |
| What does the endocrine system produce? | Hormones |
| What is the concentration of hormones controlled by? | Negative Feedback Mechanism |
| What are the major endocrine glands? | Pituitary, Thyroid, Adrenal, Pancreas, Parathyroid, Gonads |
| What organ produces insulin? | Pancreas |
| T/F: When an animal has diabetes mellitus, the beta cells do not produce enough insulin. | True |
| What does diabetes mellitus result in? | Increased blood glucose |
| What type of dog is diabetes mellitus more common in? | Older female dogs |
| What type of cat is diabetes mellitus more common in? | Male cats |
| What are the main clinical signs of Nonketotic diabetes mellitus? | PD/PU, Dehydration, Polyphagia, Weight loss, Hepatomegaly, Cataract development |
| What are the additional signs for ketotic diabetes mellitus? | Depression, weakness, vomiting, acetone breath, coma |
| T/F: Many cases of diabetes insipidus are idiopathic | True |
| What are the two types of Diabetes insipidus? | Central, Nephrogenic |
| What is the cause of nephrogenic? | Kidney disfunction |
| What is the main sign of diabetes insipidus? | PU/PD |
| What type of test is performed to diagnosed diabetes insipidus? | Water deprivation test |
| What is used to treat diabetes insipidus? | Synthetic ADH |
| Where are the adrenal glands located in relation to the kidneys? | Dorsal and cranial |
| What are the adrenal glands embedded in? | Perirenal fat |
| What two hormones do the adrenal glands produce? | Glucocorticoids and Mineralocorticoids |
| What is hypoadrenocorticism also known as? | Addison's disease |
| What species does Addison's disease occur in? | Dogs |
| What is hyperadrenocorticism also called? | Cushing's Syndrome |
| Which animal is hyperadrenocorticism common in? | Middle-aged female dogs |
| What percent of cases of hyperadrenocorticism are caused by a pituitary gland tumor? | 85% |
| What percent of cases of hyperadrenocorticism are caused by a adrenal gland tumor? | 15% |
| What is the main clinical sign of an animal with hyperadrenocorticism? | Abdominal enlargement |
| What processes does the thyroid gland control? | Metabolic |
| What type of animal is hypothyroid disease common in? | Middle-aged female dogs |
| What hormone is inadequately produced with hypothyroid disease? | T4 |
| What percent of hypothyroid disease cases are due to idiopathic thyroid atrophy compared to lymphocytic thyroiditis? | 50/50 |
| What are the clinical signs of hypothyroid disease? | Lethargy, mental dullness, Weight gain, bilaterally symmetric alopecia, recurrent skin infections, cold intolerance, constipation |
| How is hypothyroid disease diagnosed? | Blood sample |
| T/F: The treatment for hypothyroid disease is life-long hormone replacment | True |
| Which animal is hyperthyroid disease mostly seen in? | Middle-aged to older cats |
| T/F: Hyperthyroid disease is the most common endocrine disorder in cats | True |
| What percent of hyperthyroid disease is caused by benign adenomas? | 98% |
| What is the other 2% of hyperthyroid disease caused by? | Malignant adenocarcinomas |
| What are the clinical signs of hyperthyroid disease? | Unkempt hair coat, palpable thyroid slip, weight loss, polyphagia, vomiting and diarrhea, tachycardia, heart murmur, Increased blood pressure, hyperactivity, restlessness to aggressive behavior |
| What are the methods used to diagnose hyperthyroid disease? | Blood samples, ultrasound |
| What are the treatment methods for hyperthyroid disease? | Surgical removal of nodule, radioactive iodine-131, methimazole-anti-thyroid drug therapy |