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VET 201 Week 4

Research Variables: Intrinsic and Extrinsic Factors

QuestionAnswer
T/F: If more than one variable changes at a time, the cause and effect is unclear. True
What type of factors are genotype, age, and sex? Intrinsic factors inherent to the animal
What type of factors are environment, diet, and infectious agents? Extrinsic factors that are external to the animal
T/F: All variables may affect an animal's physiology and behavior True
What determines the biologic responses of individuals? Genetic composition
What is the most common cause of genetic differences? Human error
What is the goal of stock integrity? Minimize the effect of genetic drift
What are intrinsic factors related to neonates? Immature immune system
What are the intrinsic factors related to geriatric animals? Decreased organ function
What are the intrinsic factors related to sex? Differences in pharmacologic and toxicologic responses
What are the three categories of extrinsic factors? Physical, Chemical, and Microbial
What can low humidity cause? Ringtail
What can high humidity cause? Respiratory problems, Greasy coats
T/F: Some recordings may be used for enrichment if approved True
What are the two most common lighting cycles? 12:12 and 14 light: 10 dark
T/F: Red lights should never be used False
T/F: Reducing stress can result in more accurate data. True
What are the three chemical extrinsic factors? Xenobiotics, Food, Water, Bedding, Pharmaceutical agents
What type of bedding is not reccomended? Softwood
What is one of the most obvious factors that can affect research integrity? Microbes
How does direct microbial contact usually occur? Aerosolized or Fecal-oral route
Which environment does indirect microbial contact occur? Microenviroment
What is a living thing that carries disease causing organism? Vector
What is a nonliving material that can transmit disease? Fomite
What is it called when a neonate is transferred pathogens from a parent? Vertical transmission
What is it called when an infected animal transfers the pathogen to a naïve animal? Horizontal transmission
T/F: Quality husbandry is the most important part of disease prevention True
What are the methods of colony health surveillance? Histopathology, Parasitology, Serology, Molecular biology, Microbiology
Which colony health surveillance involves gross and microscopic examination of tissues and organs from asymptomatic and clinically ill animals? Histopathology
Which colony health surveillance involves a Polymerase chain reaction? Molecular Biology
Which colony health surveillance involves inoculating agar and/or broth with animal or environmental samples? Microbiology
Which colony health surveillance is the primary method? Serology
T/F: Both antibody and antigen assays are available for serologic testing. True
How long do sentinel animals need to develop an antibody response? 7 to 14 days
How long after exposure should serology sampling occur? 2 to 3 weeks
Sentinels should not be kept longer than how many months? 3 months
Which sentinels are places in cages with research animals? Direct sentinels
Which sentinels are exposed to dirty bedding/fomites? Indirect sentinels
T/F: No diagnostic test is 100% reliable True
Created by: Acraft02
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