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VET 201 Week 4
Research Variables: Intrinsic and Extrinsic Factors
| Question | Answer |
|---|---|
| T/F: If more than one variable changes at a time, the cause and effect is unclear. | True |
| What type of factors are genotype, age, and sex? | Intrinsic factors inherent to the animal |
| What type of factors are environment, diet, and infectious agents? | Extrinsic factors that are external to the animal |
| T/F: All variables may affect an animal's physiology and behavior | True |
| What determines the biologic responses of individuals? | Genetic composition |
| What is the most common cause of genetic differences? | Human error |
| What is the goal of stock integrity? | Minimize the effect of genetic drift |
| What are intrinsic factors related to neonates? | Immature immune system |
| What are the intrinsic factors related to geriatric animals? | Decreased organ function |
| What are the intrinsic factors related to sex? | Differences in pharmacologic and toxicologic responses |
| What are the three categories of extrinsic factors? | Physical, Chemical, and Microbial |
| What can low humidity cause? | Ringtail |
| What can high humidity cause? | Respiratory problems, Greasy coats |
| T/F: Some recordings may be used for enrichment if approved | True |
| What are the two most common lighting cycles? | 12:12 and 14 light: 10 dark |
| T/F: Red lights should never be used | False |
| T/F: Reducing stress can result in more accurate data. | True |
| What are the three chemical extrinsic factors? | Xenobiotics, Food, Water, Bedding, Pharmaceutical agents |
| What type of bedding is not reccomended? | Softwood |
| What is one of the most obvious factors that can affect research integrity? | Microbes |
| How does direct microbial contact usually occur? | Aerosolized or Fecal-oral route |
| Which environment does indirect microbial contact occur? | Microenviroment |
| What is a living thing that carries disease causing organism? | Vector |
| What is a nonliving material that can transmit disease? | Fomite |
| What is it called when a neonate is transferred pathogens from a parent? | Vertical transmission |
| What is it called when an infected animal transfers the pathogen to a naïve animal? | Horizontal transmission |
| T/F: Quality husbandry is the most important part of disease prevention | True |
| What are the methods of colony health surveillance? | Histopathology, Parasitology, Serology, Molecular biology, Microbiology |
| Which colony health surveillance involves gross and microscopic examination of tissues and organs from asymptomatic and clinically ill animals? | Histopathology |
| Which colony health surveillance involves a Polymerase chain reaction? | Molecular Biology |
| Which colony health surveillance involves inoculating agar and/or broth with animal or environmental samples? | Microbiology |
| Which colony health surveillance is the primary method? | Serology |
| T/F: Both antibody and antigen assays are available for serologic testing. | True |
| How long do sentinel animals need to develop an antibody response? | 7 to 14 days |
| How long after exposure should serology sampling occur? | 2 to 3 weeks |
| Sentinels should not be kept longer than how many months? | 3 months |
| Which sentinels are places in cages with research animals? | Direct sentinels |
| Which sentinels are exposed to dirty bedding/fomites? | Indirect sentinels |
| T/F: No diagnostic test is 100% reliable | True |
Created by:
Acraft02
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