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Vet 126 Drugs

Acepromazine - Phenothiazine tranquilizer - decreases activity of RAC - antiemetic - antiarrhythmic - antihistamine - splenic congestion - blocks central and alpha-1 adrenergic activity - decreases platelet functin - may see paradoxical excitation
Diazepam - Benzodiazepine - cannot be stored in plastic - light sensitive - precipitates may form when mixed with other liquid medications - IV form in acute control of seizures
Midazolam - Benzodiazepine - water soluble - combination premedication is common, esp. narcotics - mixes well with other anesthetic agents
Zolazepam - Benzodiazepine - component of Telazol
Lorazepam - Benzodiazepine - emergency adjunct anticonvulsant in dogs
Clonazepam - Benzodiazepine - occasionally used adjunct anticonvulsant in dogs
Flumazenil ANTAGONIST to Benzodiazepines
Xylazine - Thiazine derivative - cannot be used in conjunction with epinephrine - vomiting - bloat - additive effects: hypotension, CNS depression
Medetomidine - Thiazine derivative - approved for use in dog only - 2 isomers - diuretic effect - combination therapy with opioids and parasympatholytics
Detomidine - Thiazine derivative - formulated mainly for equine - fatal drug interaction can occur with IV potentiated sulfa antibiotics
Dexmedetomidine - Thiazine derivative - isomer of medetomidine
Yohimbine ANTAGONIST to Thiazine derivatives - Xylazine and Detomidine
Tolazoline ANTAGONIST to Thiazine derivatives - Xylazine and Detomidine
Atipamezole ANTAGONIST to Thiazine derivatives - Medetomidine
Morphine - Opioid - basis from which other opioids are judged - sedative effect in dogs and primates
Oxymorphone - Opioid - 10x more potent than morphine - cats can be hyperexcitable at higher dose - very expensive
Hydromorphone - Opioid - 5x more potent than morphine - commonly used in vet. med. - relatively safe in all species
Fentanyl - Opioid - 250x more potent than morphine - primarily used as transdermal patch for severe pain relief
Meperidine - Opioid - 1/8th potency of morphine - needs to be given IV slowly - horses can experience PVC
Buprenorphone - Opioid - 30x more potent than morphine - good for pocket pets - partial agonist/antagonist - may not see full effect in some species
Butorphanol - Opioid - 4-7x more potent than morphine - synthetic opioid/antagonist - approved for use in dog for suppression of non-productive cough - tolerance buildup with sequential repeated use
Naloxone ANTAGONIST to Opioids
Atropine - Parasympatholytic - crosses blood brain barrier - crosses placenta - decreases tear production
Glycopyrrolate - Parasympatholytic - does not cross blood brain barrier - does not cross placenta - can cause transient second degree AV block when given IV
Created by: hbrandt