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VET 201 Week 1
Mice & Rats
Question | Answer |
---|---|
What is an outbred stock of mice? | heterogeneous; every mouse is genetically different |
What is an inbred stock of mice? | genetically identical |
What type of mice would you order if you needed mice free of all detectable microflora? | Germ‐free mice |
What type of mice would you order if you needed mice free of a defines list of pathogens? | Specific pathogen‐free mice |
What federal organization requires the safety of a product to be proven in animal models prior to being marketed for humans? | FDA |
T/F: Mammary tissue is only found on the abdomen of mice | False—mammary tissue can be found all around the mouse body, including the sides and back. |
Which pheromone effect are you taking advantage of if group-housed female mouse are exposed to male mouse urine to synchronize estrous? | Whitten effect |
Which type of nesting material should be avoided in nude mice, and why? | Cotton nesting material, it can cause damage to their eyes (due to a lack of eyelashes) or can wrap around their toes. |
T/F: Mice must be anesthetized for retro-orbital blood collection or injections | True |
What is a chimera? | A mouse that has tissues or cells derived from two different embryonic stem cell sources |
What does CRISPR stand for? | Clustered Regularly Interspaced Short Palindromic Repeats |
What is a minimally invasive tissue collection technique for genotyping that does not require anesthesia or analgesia? | Ear punching |
What is bacteria associated with chronic active hepatitis? | Heliobacter hepaticus |
What is a parvovirus that targets intestinal and lymphoid tissue? | Mouse minute virus |
What is a hair chewing of vibrissae on head region? | Barbering |
What are Syphacia and Aspicularis? | Pinworms |
What is a poxvirus that can lead to amputation of feet and tail? | Ectromelia virus |
What are Myobia and Mycoptes? | Mites |
What is a coronavirus that is highly contagious; enteric and respiratory patterns? | Mouse hepatitis virus |
What is a genetically linked skin syndrome found frequently in C57BL/6 mice? | Ulcerative dermatitis |
What is the cause of scaly skin disease in nudes? | Corynebacterium bovis |
What disease is found in association with water, not a normal part of flora? | Pseudomonas aeruginosa |
Which of the following are outbred stocks of rats? | Sprague-Dawley, Wistar, Long-Evens |
Which genetic classification is useful for modeling natural population diversity? | Outbred stock |
_____ animals colonized only with a know population of microflora. | Gnotobiotic |
Which is NOT an acceptable reason to singly house animals of a social species? | Cost |
What is the usual gestation period of a rat? | 21-23 days |
Which of the following is INCORRECT regarding nutrition? | Rats drink an average of 10 to 12 mL of water per day |
As a general guideline, up to what percent of the circulating blood volume can be withdrawn every 2 to 3 weeks from normal healthy animals with minimal effect? | 10% |
If a procedure in known to cause pain in humans, if must be assumed to also cause pain in rats unless ________. | Proven othrwise |
Recommended methods for administration of intraperitoneal injections in rats is.... | Lower right abdominal quadrant |
Recommended methods for the individual identification of adult rats include all except | Toe clipping |
What is the name of the AVMA guidance document for members of the veterinary profession who carry out or oversee the euthanasia of animals? | Guidelines for the Euthanasia of Animals |
What is Trichophyton mentagrophytes? | Ringworm |
What is Radfordia ensifera? | Rat fur mites |
What are gross lesions include miliary pale foci of the liver, abdominal distention, and megaloilietis? | Clostridium piliforme |
What are "Red tears"? | Chromodacryorrhea |
Which disease is associated with low housing humidity? | Ringtail |
What is the pinworm species for which the perianal tape test may be diagnostic? | Syphacia |
Which bacteria is histologically visible between and parallel to the cilia of respiratory epithelium? | CAR bacillus |
What is the etiologic agent of rat-bite fever? | Streptobacillus moniliformis |
What is also known as Rat Coronavirus? | Sialodacryoadenitis |
What is a bacteria that induces chronic respiratory disease and a "cobblestone" appearance of the lungs? | Mycoplasma pulmonis |
What is the predilection for actively dividing cells? | Parvoviruses |
What is a zoonotic tapeworm in rats? | Rodentolepis nana |
What is a common tumor of aged rats? | Pituitary adenoma |