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clin path review

more clin path

tylenol toxicity in dogs may cause the what in erythrocytes? heinz bodies
T or F the PCV is 1/3 the value of the Hgb value? False
denatured Hgb found in an erythrocyte is known as? heinz body
the tx for FIA is? doxycycline
neutrophilia means? increased # of neutrophils
which tube is unsuitable for chemistry tests? purple
which tube should be used for clotting tests? blue
which type of blood cell is the most immature wbc found in the bone marrow and rarly to never found in the blood stream? myeloblast
which type of erythrocyte may be found in the blood stream. this red blood cell has a speckled appearance w/ new methylene blue stain? reticulocyte
reticulocytes are larger or smaller than a mature RBC? larger
reticulocytes contain what? residual RNA remanents
more oxygen molecules are released under which conditions? increased temp. and increased DPG production
hematopoiesis means? production of all blood cells
carboxyhemoglobin means? Hgb has a higher affinity for CO than O2
leukocytosis means? increased # of WBC
hypochromasia? erythrocytes stain pale pink
polychromasia? blue staining
anisocytosis? variation in erythrocyte size
basophilic stippling is often associated w/? lead posioning
dark staining, basophilic "spot", found in erythrocytes and is a RNA remanent? howell-jolly body
fragmented RBC's? schistocytes
which type of leukocyte is not normally sampled in an excited animal? resulting in an increase in TWBC marginated neutrophil
vacutainer system order of draw? tiger, red, blue, green, purple, gray
syringe method order of draw? blue, green, purple, gray, red, tiger
acanthocyte? irregular elongated projections from the cell margins
hypersegmented neutrophil? aged neutrophil
poikilocytosis? variation in cell shape
hemoptysis? coughing up blood
epitaxis? bleeding from nose
deficiency of platelets can cause what? petechiation
eccymosis? bruising
normal platelet count and life span? 200,00-500,000; 7-10 days
how do you count platelets? from a blood smear count 10 fields at 100x, take avg. and multiply by 15,000
3 common causes of thrombocytopenia? increase destruction, bone marrow defects, increased consumption
methemoglobin? the FE molecule is oxidized to FE(^+3)
life span os an erythrocyte in a dog? 110 days
neutrophil barr body? x chromosome remanent
rouleaux "stacking" of RBC's
normocytic? normal sized (mature) erythrocytes
hypochromic? decrease in staining intensity b/c of decrease in Hgb=iron deficiency
echinocytes (burr cells)? RBC's look like pom poms sign of crenation
spherocytes suggest what? immune mediated hemolytic anemia
spherocyte? smaller, dark, and lack central pallor RBC's
aggultination? clumping of RBC's
name 3 finding that may be found in a normal blood smear from a cat? rouleaux, howell-jolly bodies, and doehle bodies
howell-jolly body? basophilic nuclear remanents
where are doehle bodies found? wbc's
where are heinz, howell-jolly, rouleaux, and basophilic stippling found? rbc's
crenation? destruction of RBCs
reticulocyte? immature rbc that is larger and bluish color
other names for hemobartonella felis? (FIA) feline infectious anemia and mycoplasma felis
other name for hemobatonella canis mycoplasma canis
anaplasma marginale is transmitted how? tx? ticks, needles; tetracylines, imidiocarb
anaplasma phagocytophilium is transmitted how and how do you test for it? ticks; idexx 4dx
babesia is transmitted how and treated with what? ticks; imidiocarb
cytauzoon felis is transmitted how? clinical signs? tx? morphology? ticks; hemolytic anemia, jaundice, fever, death; no treatment; like a ring
Pyruvate kinase deficiency in basenji causes what? decrease in ATP and RBCs don't live as long
total plasma protein is measured w/ what device and in what units? refractometer; g/dl
MCV? MCH? MCHC? mean corpuscular volume (RBC size), mean corpuscular Hgb, mean corpuscular Hgb concentration
PCV normal range? 37-55%
how do you find the TWBC count using the hemocytometer? total # in grid + 10% of total # in grid x 100
how do you find the TRBC count? it will be given
how do you perform a WBC differential? manually from a blood smear %
how do you calculate the absolute WBC numbers? TWBC count x 100% of WBC diff.
how do you calculate the MCV? normal range? PCV x 10/TRBC count =fl; normal range is 66-77fl
what terms are used to describe MCHC? hypchromic or normochromic
how do you calculate MCHC? Hgbx100/PCV= gm/dl
what terms are used to describe MCV? microcytic, macrocytic, or normocytic
how do you calculate MCH? Hgbx10/RBC(10^6)= pg(picograms)
macrocytic + hypochromic = ? regenerative anemia ^reticulocytes
normocytic + normochromic =? non-regenerative anemia few reticulocytes and indicates a bone marrow defect
microcytic + hypochromic =? iron deficiency
3 major causes of high WBC? bacterial infection (sepsis), non septic inflammation (pancreatitis, toxins, snake bite), and neoplasms
regenerative left shift? elevated TWBC, bands are less or equal to segs
degenerative left shift normal or lower TWBC, bands exceed segs
6 changes seen in stress/ corticosteroid response? moderate leukocytosis, mature neutrophilia, lymphopenia and eosinopenia, no left shift, monocytosis, neutro's go to circulating pool fast
Created by: supersam1314



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