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Pharmacology Drugs

TermDefinition
Cholinergic Agents Mimic acetylcholine and stimulate receptor sites of the parasympathetic system; treats urinary retention, controls vomiting, and stimulates GI motility
Cholinergic Blocking (Anticholinergic) Agents Blocks actions of acetylcholine at muscarinic receptors of the parasympathetic nervous system; prevent/treats bradycardia, decreases GI motility
Adrenergic (Sympathomimetic) Agents Bring about action at receptors mediated by epinephrine or norepinephrine; treats glaucoma, urinary incontinence, and stimulates the heart to beat during cardiac arrest
Adrenergic Blocking Agents Disrupts activity of the sympathetic nervous system; includes alpha blockers, beta blockers, and ganglionic blockers
Tranquilizers Depresses the CNS by blocking/stimulating receptors and interfering with nerve impulses; sedative, analgesic, and tranquilization properties
Barbiturates Used as sedatives, anticonvulsants, general anesthetics, and euthanasia agents; nonreversible; potent depressing effects of the cardiac and pulmonary systems (long-acting = 8-12 hours, short-acting = 45 min-90 min, ultrashort-acting = 5-30 min)
Dissociative Agents Depress the thalamus and cerebral cortex; the animal will feel dissociated from their body and be ataxic and hyper-responsive
Opioid Agonists Produces analgesia and sedation; 4 classes of receptors (mu, kappa, sigma, and delta); class II controlled substances
Opioid Antagonists Blocks effects of opioids by binding with opiate receptors, displacing narcotic molecules already present, and further narcotic binding at the sites; usually administered IV
Neuroleptanalgesics Consists of an opioid and a tranquilizer; used for sedation, restraint, and anesthesia
Inhalant Anesthetics Converted from a liquid to a gas by an anesthetic vaporizer; produces unconsciousness, analgesia, and muscle relaxation
CNS Stimulants Used for respiratory depression or arrest
Neuromuscular Blocking Drugs Interferes with neuromuscular transmission of impulses and are used as an adjunct to general anesthesia; also known as muscle relaxants
Expectorants Drugs that liquify and dilute viscid secretions of the respiratory tract, thereby helping in evacuation of those secretions
Mucolytics Alters the chemical composition of mucus through the breakdown of chemical bonds
Antitussives Inhibit/suppress coughing by depressing the cough center in the brain
Decongestants Reduces congestion of nasal membranes by reducing associated swelling
Antihistamines Blocks the effects of histamines; inhibits effects or spreading of the inflammatory process
Corticosteroids Treats inflammatory, pruritic, and immune mediated diseases
Loop Diuretic Blocks the mechanism that transports sodium, thus inhibiting the tubular reabsorption of sodium and chloride; the strongest and most commonly used diuretic
Osmotic Diuretics Promotes dieresis recess by increasing the pressure in the kidney tubules, which limits reabsorption
Thiazide Diuretics Blocks reabsorption of sodium, chloride, and water
Potassium-Sparing Diuretics Blocks the action of aldosterone, which is responsible for the reabsorption of sodium in the excretion of potassium
Carbonic Anhydrase Inhibitors Decreases formation of carbonic acid in water; the weakest diuretic; not as effective as others
Angiotensin-Converting Enzyme (ACE) Inhibitors Blocks conversion of angiotensin I - angiotensin II, decreases aldosterone secretion, reduces peripheral arterial resistance, and alleviates vasoconstriction
Class 1A Antiarrhythmic Drugs Depresses myocardial excitability, prolongs the refractory period, decreases automaticity, and increase conduction times
Class 1B Antiarrhythmic Drugs Prevents depolarization and decreases cell automaticity
Class II Antiarrhythmic Drugs Beta-Adrenergic blockers (may only block beta1 receptors, only beta2 receptors, or they may block both types)
Class IV Antiarrhythmic Drugs Blocks the channels that permit entry of calcium ions through the cardiac cell membrane
Vasodilator Drugs Dilates arteries (arteriolar dilator), veins (venodilator), or both (combined vasodilator)
Emetics Drugs that induce vomiting; removes around 80% of the stomach contents
Antiemetics Used to prevent/control vomiting
Gastrointestinal Prokinetics/Stimulants Increases the motility of part(s) of the GI tract, which enhances the transit of material through the tract
Parasympathomimetics Used to induce contraction of the intraocular smooth muscle (miosis), which helps to reduce IOP
Sympathomimetics Decreases IOP
Topical Corticosteroids Used with other treatments for localized itching or inflammatory conditions
Macrolides Inhibits protein synthesis by penetrating the cell wall and binding to the 50S ribosomes subunits in susceptible bacteria
Penicillins Inhibits mucopeptide synthesis in the cell wall, which results in a defective barrier and an osmotically unstable spheroplast; discovered in 1928 by Sir Alexander Fleming
Tetracyclines Inhibits protein synthesis by reversible bind to 30S ribosomal subunits of susceptible organisms, thereby preventing binding to this ribosomes of aminoacyl transfer-RNA; aniinflammatory and immunomodulating effects
Opiod Analgesics Relieves pain by binding with specific receptor sites in the brain, spinal cord, and peripheral tissue
Inactivated Vaccine Involves killing the organisms with chemicals that leave the antigens mostly unchanged
Live Vaccine Prepared from live microorganisms/viruses; may be fully virulent or avirulent
Modified Live Vaccine Organisms undergo a process (attenuation) to lose their virulence so that when introduced to the body via inoculation, they cause an immune response instead of disease
Type I Recombinant (Subunit) Vaccine Derived by inserting a foreign gene from a specific pathogen into a recombinant organism
Type II Recombinant (Gene-Deleted) Vaccine Involves deletion of specific genes from a pathogenic organism
Type III Recombinant (Vectored) Vaccine Derived from the insertion of a specific pathogenic genetic material into a nonpathogenic or gene-deleted organism
Toxoid Produces immunity to a toxin rather than a bacterium or a virus
Antitoxin A specific antiserum aimed at a toxin that contains a concentration of antibodies extracted from the blood serum or plasma of a hyperimmunized, healthy animal
Antiserum Contains specific antibodies extracted from a hyperimmunized animal or an animal that has been infected with microorganisms that contain antigens
Autogenous Vaccine Contains organisms isolated from an infected animal on a farm where a disease outbreak is occurring
Mixed Vaccine Contains a mixture of different antigens
Created by: KaleighMichelle
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