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Pharmacology
Chapter 11 Drugs Used in Skin Disorders
| Question | Answer |
|---|---|
| What is the largest organ of the body? | The skin. Part of the integumentary system. |
| What are the functions of skin? | Barrier; senses heat, cold, pain, touch, pressure, other sensations; regulate body temperature; immunologic defense; produces vitamin D3; reservoir for electrolytes & other substances; limited role in excretion. |
| Describe the three layers of skin. | Epidermis (basal, spinous, granular, clear, horny/cornified)--superficial; dermis (corium)--thickest part of skin; hypodermis (subcutis or panniculus)--deepest part of skin. |
| What are products of skin? | hair, other keratinized structures like nails, horns, nasal pads & footpads. |
| List the common ingredients of topical antiseborrheics. | natural oils, essential fatty acids, sulfur, salicylic acid, coal tar, benzoyl peroxide. |
| Describe the use of topical antipruritics. | Cleanse the skin, anesthetic to relieve pain/itching. |
| Explain the use of fatty acid supplements. | Affect arachidonic acid levels and the production of prostaglandins in the body, which can reduce inflammation & pruritis. |
| Explain the use of astringents. | Used to treat superficial skin problems, and to dry moist areas. |
| Explain the use of skin antiseptics. | To clean the skin. |
| Describe the wound healing process. | Inflammation--begins w/ hemorrhage, limited by vessel contractioin & constriction; debridement--begins 6 hrs after injury, neutrophils & monocytes to wound; repair--forms clot, 3-5 days after; maturation--end of healing, period of remodeling. |
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