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Rhodococcus equi

infectious disease

QuestionAnswer
Rhodoccus equi general info gram+ rods or cocci. Salmon-pink, mucoid, non-hemolytic colonies. Aerobic, non-motile. CAMP test pos. Major respiratory pathogen in foals
Clinical condition: Foals Suppurative bronchopneumonia and pulmonary abscessation, abdominal abscesses, osteomyelitis
Clinical condition: horses superficial abscessation, abdominal abscesses, osteomyelitis
clinical condition: pig, cattle Mild cervical lymhadenopathy
clinical condition: cats subcutaneous abscessation, mediatinal granulomas
clinical conditions: immunosuppressed humans penumonia
clinical signs hematogenous granulomatous or suppurative inflammation of mesenteric LN and osteomyelitis and arthritis. sudden onset of fever. anorexia. coughing, dyspnea, weight loss, exercise intolerance. loud/moist rales
acquired via inhalation of dust. may be present in high numbers in horse feces.
env influences dry weather, poor grass coverage.
pathogenesis survive and multiply in macrophage. encodes several proteins (VapA)
virulence principally associated w/ large plasmid, VAP.
equine suppurative bronchopneumonia diagnosis differentiating lower respiratory tract infections w/ WBC, Fibrinogen, radiography, ultrasonography. Bacterial culture from tracheobronchial aspirate, tissue. PCR from tracheobronchial aspirate, tissue
equine suppurative bronchopneumonia treatment combination of oral rifampin and macrolide for up to 10wk. response of therapy monitored by radiography/ultrasonagrophy and plasma fibrinogen. supportive therapy
equine suppurative bronchopneumonia control no vaccine. screening foals twice a wk by clinical examination. prevention of dust inhalation. limit foal density. limit time spent indoor.
Created by: ejohnson17
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