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corynebacterium spp

infectious disease

QuestionAnswer
corynebacerium spp general info small, pleomorphic, gram +. When stained appear as Chinese characters. Fastidious, need enriched media. catalse+, oxidase -, non spore forming, pathogenic form non motile.
corynebacerium spp pathogensis opportunistic. pyogenic organisms. produce diptheria toxin. produce urease
C.bovis iso from teat canal of healthy cattle
C.presudotuberculosis iso can survive and replicate in phagocytes
corynebacerium spp virulence linked to cell wall lipid and an exotoxin PLD and CP40
Role of CP40 induces strong immune response, provide protection
Role of PLD enhance survival and multiplication
conditions affecting secretion of diptheria toxin 1.EC iron levels in tissues of respiratory tract 2.presence of specific beta phage 3.inhibits host protein syn
Caseous lymphadenitis causative agent C.pseudotuberculosis
Caseous lymphadenitis chronic suppurative condition of sheep, goat, rarely cattle. incubation 3 mo. abscessation and enlargement of superficial and internal LN
Caseous lymphadenitis transmission skin wounds, arthropod bites, dips
Caseous lymphadenitis clinical signs superficial, subcutaneous abscesses, usually in head/neck/ spread by ruptured abscesses. Hematogenous spread=infect LN. Thrift and pneumonia.
Caseous lymphadenitis sp infect goats
Caseous lymphadenitis treatment therapy usually ineffective due to intracellular survival ability of bacteria and inability of drugs to penetrate into abscesses
Caseous lymphadenitis control pre-importation screening, quarantine for 3 mo. infected animals slaughtered. vaccine available
Ulcerative lymphangitis causative agent C.pseudotuberculosis in horse. rarely in cattle
Ulcerative lymphangitis transmission skin wounds, arthropod bites, contact of infected animals.
Ulcerative lymphangitis clinical signs lymphangitis of lower limb or abscessation of pectoral region (pigeon fever).
lymphangitis slow and chronic. lymphatic vessels swollen and firm. nodules form along length. edema develops in affected limb and ulcerated nodules exude a thick, odorless, greenish blood tinged pus.
bovine pyelonephritis causative agent C.renale. iso from healthy cattle vulva, vagina, prepuce
bovine pyelonephritis predisposition stress of parturition, short urethra.
bovine pyelonephritis causes pyelophritis how ascending infection from bladder through ureters. chronic infection lead to extensive renal damage
bovine pyelonephritis clinical signs fever, anorexia, decreased milk prod, restlessness and kicking in abdomen (renal pain). dysuria and blood tinged urine. UTI. unilateral thickening of ureters and enlarged kidneys.
Ulcerative balanoposthitis causative agent C.renale in sheep and goat. castrated sheep more prone.
Ulcerative balanoposthitis clinical sign ulceration around prepucial orifice w/ brownish crust developing over lesion.
how does C.renale cause mucosal irritation and ulceration hydrolyses urea into ammonia
Ulcerative balanoposthitis predisposing factor high protein intake b/c high urea level in urine
Ulcerative balanoposthitis untreated cases may result in total occlusion of preputial orifice
Created by: ejohnson17
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