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L7 - Behavior Mods
Clin Pharm Ex 1
| Question | Answer |
|---|---|
| Monoaminergic NTs | Serotonin, NE, & DA |
| GABAergic NTs | gamma-aminobutyric acid |
| Mild sedative & anxiolytic used to manage fear, phobia, & anxiety | Benxodiazepines |
| Benzo can be used with... | TCAs or SSRIs |
| When ending Benzo tx, be sure to... | withdrawal slowly so don't precipitate seizures |
| Benzos should never be used in... | aggressive patients |
| H2O insoluble Benzo that can induce hepatic toxicity | Diazepam |
| Slow onset, longer acting Benzo that can also be used as an apetite stimulant in cats | Oxazepam |
| Serotonin non-sedating anxiolytic used to manage fear, phobia, & anxiety | Buspiron |
| Buspiron can be coupled with which drug to tx complex behavioral probs? | Fluoxetine |
| Buspiron requires what to be clinically effective? | several weeks of admin |
| Buspiron shouldn't be used in... | patients w/severe hepatic or renal dz |
| Antidepressant drugs | TCAs, SSRIs, & MAOIs |
| Amitriptyline is used to tx what in dogs? | aggression, self-mutilation, & separation |
| Amitriptyline is used to tx what in cats? | psychogenic alopecia, excessive vocalization, & idiopathic interstitial cystitis |
| TCAs in general cannot be used with... | MAOIs |
| Most selective TCA | Clomipramine |
| Clomipramine is used to tx what in dogs? | separation anxiety, OCD, & dominance aggression |
| Clomipramine is used to tx what in cats? | psychogenic alopecia & urine spraying |
| TCA that also has MAO activity | Imipramine |
| Imipramine is used to tx... | inappropriate urination, incontinency, & ejac dysfxn in horses |
| TCA that affects NE & 5-HT reuptake, potent H1 & H2 anti-histamine effects | Doxepin |
| Doxepin is used to tx... | psychogenic dermatitis related to anxiety |
| SSRI used to tx aggression & acral-lick dermatitis in dogs | Fluoxetine |
| Fluoxetine is used to tx what in cats? | spraying, psychogenic alopecia, & aggression |
| SSRI used to tx aggression & sterotypy in dogs | Paroxetine |
| Sterotypy is best tx with... | environmental changes |
| Paroxetine is used to tx what in cats? | spraying & aggression |
| Amitriptyline SE include... | sedation, mydriasis, urinary retention |
| Clomipramine SE include... | sedation, regurg, anticholinergic signs |
| Imipamine SE include... | weakness, ataxia (horses) |
| Doxepin SE include... | antimuscarinic effects |
| Fluoxetine SE include... | ↑ anxiety, irritability, altered sleep pattern |
| Paroxetine SE include... | anorexia & constipation |
| Sertaline & Fluvoximine are SSRIs used to tx what in cats & dogs? | aggression, OCD, & anxiety |
| Sertaline & Fluvoximine SE include... | anorexia, constipation, behavioral & sleep pattern changes |
| SSRI that's also an a1 antag & weak 5-HT2a antag, | Trazadone |
| Trazadone is used in dogs to tx... | post surgery anxiety |
| Trazadone SE include... | behavioral and sleep pattern changes |
| MAO-B oxidatively deaminates... | DA, NE, Epi, & 5-HT |
| MAO-B inhib, NE & 5-HT reuptake inhib, & D2 receptor inhib | Selegiline |
| Selegiline is best used in... | cats |
| Selegiline is used to tx what in cats? | aggression, ↓ appetite, compulsive licking, excessive vocalization, & cognitive dysfxn |
| Selegiline SE include... | stereotypy in dogs (rare) |
Created by:
Dr_B.Phillips22
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