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Synonym: Soremuzzle
Arthropod-borne disease of ? and is characterized by 3 things: SHEEP. Congestion, Edema, and Hemorrhage
Hosts: Sheep and white-tailed deer
Transmission: NONCONTAGIOUS. Biological Vectors (Culicoides spp.)->usually feed at dawn and dusk, and require standing water in which to breed. Transplacental after AI with infected semen
Replicates: Hematopoietic cells and endothelial cells of the blood vessels-> VIREMIA
Length of viremia: Sheep: 14-28 days. Cattle: 70-90 days.
Clinical signs in cattle: oral lesions. SUSPECTED RESERVOIR HOSTS
Clinical sings in sheep: Fever, unlcerated mouth, profuse salivation and frothing. Coronitis (lameness) and CYANOSIS OF TONGUE (bluetongue) = vasiculitis and abortion
Morbidity vs. Mortality: 80% vs. 50%
Neurological effects in fetal sheep: hydranencephaly (50-58 days). Porencephaly (75-78%). Glial nodules (over 100 days)
What do you use to isolate the virus? Heart blood (washed RBCs or buffy coat)
Prevention method: put sheep in barns at dusk to avoid culicoides
Vaccination: NO ATTENUATED VACCINES with pregnant animals. Also suspected that GENETIC REASSORTMENT with the wild type virus may occur in Culicoides spp. yielding new virus strains
Created by: lkollmeier