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Bluetongue
Reoviridae
| Question | Answer |
|---|---|
| Synonym: | Soremuzzle |
| Arthropod-borne disease of ? and is characterized by 3 things: | SHEEP. Congestion, Edema, and Hemorrhage |
| Hosts: | Sheep and white-tailed deer |
| Transmission: | NONCONTAGIOUS. Biological Vectors (Culicoides spp.)->usually feed at dawn and dusk, and require standing water in which to breed. Transplacental after AI with infected semen |
| Replicates: | Hematopoietic cells and endothelial cells of the blood vessels-> VIREMIA |
| Length of viremia: | Sheep: 14-28 days. Cattle: 70-90 days. |
| Clinical signs in cattle: | oral lesions. SUSPECTED RESERVOIR HOSTS |
| Clinical sings in sheep: | Fever, unlcerated mouth, profuse salivation and frothing. Coronitis (lameness) and CYANOSIS OF TONGUE (bluetongue) = vasiculitis and abortion |
| Morbidity vs. Mortality: | 80% vs. 50% |
| Neurological effects in fetal sheep: | hydranencephaly (50-58 days). Porencephaly (75-78%). Glial nodules (over 100 days) |
| What do you use to isolate the virus? | Heart blood (washed RBCs or buffy coat) |
| Prevention method: | put sheep in barns at dusk to avoid culicoides |
| Vaccination: | NO ATTENUATED VACCINES with pregnant animals. Also suspected that GENETIC REASSORTMENT with the wild type virus may occur in Culicoides spp. yielding new virus strains |