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Paramyxoviridae
Rinderpest. Genus Morbillivirus
| Question | Answer |
|---|---|
| Synonym: | Cattle Plague |
| Characteristic necroses and erosions? | Mucosa in the respiratory and GI trats, lymphoid, and HIGH MORTALITY |
| ONE OF THE MOST FATAL DISEASES OF CLOVEN-HOOFED ANIMALS | |
| Hosts and Transmission: | Cattle and Buffalo. Nasopharynx, nasal secretions, secretions from throat, conjunctiva, feces, urine, and milk. Transferring cattle could be carriers and are excreting the virus before they show any clinical signs. NO CARRIER STATUS in CATTLE |
| How is this different from Canine Distemper? | NO CNS signs |
| Specal affinity for what cells? | epithelial cells of URT, GIT and both T and B lymphocytes |
| Pathogenesis: | Replicates in the Palatine tonsils, mandibular and pharyngeal lnn->Viremia in 2-3 days->extensive destruction of lymphocytes in lymphoid organs->latent infections and increased susceptibility to other infectious agents |
| Clinical signs? | Peracute, acute, subacute depend on the type of cattle. Abdominal respiration with coughing (congestion of anterior lung lobes). Bloody diarrhea, dehydration, terminal hypothermia and DEATH. |
| Morbidity and Mortality rate? | near 100% |
| Immunity? | Lifelong in recovered animals |