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Foot and Mouth
Picornaviridae
Question | Answer |
---|---|
What is another name for this disease? | Aphthous fever or Epidemic Aphthae |
Who is and is NOT susceptible to this disease? | All cloven-hoofed animals are susceptible. Swine were the #1 cause of the outbreak. HORSES ARE GENETICALY RESISTANT TO FMD |
Does the virus have cross-protection amongst it's serotypes? How long can the virus survive in the stall? Stacks of Hay? Muscle of a carcass? | NO cross-protection. 14 days in the stall. 20 weeks on stacks of hay. Virus inactivated within 48 hours of slaughter but survives much longer in BONE MARROW, VISCERA, and BLOOD CLOTS |
What pH is this virus stable at? What four disinfectants can kill the virus then? | 6-9. Sodium hydroxide, Sodium carbonate (soda ash), Citric acid, and Acetic acid |
What is the main way this virus is transmitted? What are other ways that have been documented? | INHALATION. DIrect contact with meat, milk, or semen. Garbage with uncooked scraps. ASYMPTOMATIC CARRIERS or ANIMALS INCUBATING the virus can carry it for long distances. Birds and rodents via mechanical spread |
How long does it take to start shedding the virus? | Virus shedding starts 24 hours PRIOR to clinical signs! |
Where does the virus replicate before it's initial viremia in the body? | Pharynx then it moves to epithelial cells of the mucosa and skin->lesions |
What is the most common cuase of fatal FMD in young animals? | TIGER HEART: myocardical leions that are small streaks of irregular size and shape in the myocardium giving it a striped appearance |
What are the timelines for carriers? Who is NOT a carrier? | Virus can persisten in the pharynx for up to 2 years in cattle and 6 months in sheep. PIGS HAVE no CARRIER STATUS |
Who shows the most severe clinical signs? Who is subclinical? | Cattle and swine are the worst. Sheep and goats are subclinical |
Relationship between morbidity and mortality in cattle: | HIGH to <5% |
What signs are cattle showing within 24 hours? Where are vesicles present? What does the persistant fever causes? | Salivate profusely and are lame. Tongue, lips, gums and palate, teats, rumen pillars, coronary band, and interdigital areas. Abortion in pregnant animals and MASTITIS with 25% drop in milk production |
What leads to secondary bacT infections? | Ulceration of the vesicles on the oral cavity and hooves |
How are pigs affected? How is it spread in piggeries? | Fever and lameness due to ulcerations and blisters on their feet. Aerosols (urine smells) have HIGH levels of the virus |
What type of immunity do animals have that recover from this disease? | NO LIFELONG. Immunity is TYPE-SPECIFIC which means that once recovered, they can sucumb to any of the other serotypes! |
What control measures can be taken in endemic countries? | Vaccination and imposition of quarantine in an outbreak |
What control measures can be taken in disease-free countries? | NO VACCINATION. Quarantine and slaughter of infected animals, disposal of carcasses by deep burial or burning |