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Vesicular Stomatitis

Vesiculovirus of Rhabdoviridae

This is a sporadic disease of who? Cattle, horses, swine, and humans
T/F. There is cross-protection between serotypes. FALSE
Which serotypes is more virulent: Indiana or New Jersey? NEW JERSEY
How is the virus transmitted? Teat and Udder Lesions via contact with infected milking machines. Mouth lesions via ingestion of contaminated fomites.
Which is most important: mechanical or biological transmission? MECHANICAL: Houseflies
Explain the pathogenesis of this disease. Virus enters body through skin or mucosa breaks->epithelial cell destruction and interstitial edema->epithelium separated from underlying tissue->vesicle formation->spread of lesions by local extension
Pigs and Labratory animals are special pathogenetically because why? They are the only ones that SYSTEMIC and VIREMIC phase of infection is observed
What is the main clinical feature? Oral lesions with profuse salivation and anorexia
What can you do to prevent this disease from spreading? Prohibit movement of animals on affected premises for 30 days after the last clinical signs
When are vaccines available? Autogenous killed vaccines are only available during outbreaks
Created by: lkollmeier