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Retroviridae
Avian Leukosis
Question | Answer |
---|---|
What is the incidence rate in most chicken populations? | 3-20% |
What type of virus is this disease cuased by? | v-onc - |
Subgroup J is associated with... | Myeloid leukosis |
What is the cutoff to be viremic for life? | 5 days! |
How can the chicken be viremic for life? How is the virus exreted? | Virus is transmitted congenitally via the egg or horizontally within the first 5 days of life due to the development of immunological tolerance. Saliva and feces |
What happens if a chicken is infected beyond 5 or 6 days? | Horizontal transmission past the cutoff allows the chicken to devlop neutralizing antibodies, the viremia is transient, and the chicken is UNLIKELY to develop leukemia |
What are the primary target cells of this virus? What can prevent the development of lymphoid leukosis? | lymphoblasts with B lymphocyte markers. Bursectomy |
What are two clinical features that occur sporadically? | Lymphoid leukosis & Osteopetrosis |
What are two other names for Lymphoid leukosis in birds? Observed in what age chickens? | Syn. Visceral Lymphomatosis. BIG LIVER Disease. 14-30 weeks of age |
What's another name for osteopetrosis? What is characteristic of this disease? | THICK LEG. Proliferation of periosteal osteoblasts of th elong bones of the limbs. BILATERAL enlargement...Lesions are NOT neoplastic |
What is different from this disease and Marek's disease? | Tumors in multiple organs WITHOUT nerve or ocular invovlement |