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Retroviridae
Feline Sarcoma Virus (FSV)
| Question | Answer |
|---|---|
| How is this virus formed? | de novo as a recombinational event between FeLV-A and host cell proto-oncogenes |
| How does this virus become infective? | It is a v-onc+ and defective so a helper FeLV is required for replication. It is defective because the env gene is lost during recombination. ALL STRAINS causing fibrosarcomas are PSEUDOTYPES |
| T/F. Solitary fibrosarcomas in old cats (greater than 5 years old) are caused by FeSV. | FALSE |