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Retroviridae
Nonneoplastic Diseases
Question | Answer |
---|---|
Circulating immune complexes predispose cats to: | glomerulonephritis and polyarthritis |
Some persistenly viremic cats suffer from a severe lymphopenia due to...neutropenia, or both | Loss of circulating T cells\ |
What is immunosuppression characterized by in cats? | chronic gingivitis and stomatitis, feline infectious peritonitis, hemobartenollosis |
Why don't we breed viremic queens? | Most kittens born to them become viremic and die at an early age do to "FADING KITTEN SYNDROME" - failure to nurse, thymic atrophy, hypothermia |
What two tests can be used to detect the group-specific antigen, p27? | ELISA and IFA |
What does ELISA test for? What should be done with ELISA positive cats? | presence of circulating p27 antigen in plasma, whole blood, or serum. Saliva and tears can also be used. Cats should be retested within 2-3 months to determine if viremia is transient or persistent |
What does the IFA test look for? Do these positive cats stay infected for life? | p27 antigen associated with leukocytes and platelets in fixed blood smears. 97% of them stay positive for life! |
What does a positive ELISA or IFA test indicate? | only the INCREASED risk of FeLV-related diseases |
What type of cat should you never vaccinate? | Cats that were + and then later become - |
Vaccination for FeLV reduces the risk of the virus by... | 80% |