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Porcine Parvovirus

Parvoviridae

QuestionAnswer
Virtually all sows in a herd are naturally infected before their second pregnancy hence reproductive problems are observed mostly in... primiparous gilts
SMEDI present and how many serotypes are present? ONE
What are two ways the virus can be transmitted? Oronasal and venereal transmission due to infected boars shedding the virus in the semen for a couple of weeks
Are all embryos infecetd at the same time in transplacental infection? NO...each one has a different placenta but a spread eventually occurs and as a result DEATH AT DIFFERENT STAGES OF PREGNANCY IS TYPICAL
Where does PPV have a predilection site for? mitotically active cells, esp capillary endothelial cells and leukocytes
What is the HALLMARK of PPV infection? small litters with dead fetuses (mostly mummified, some stillborn) and healthy piglets
T/F. Abortions are common. FALSE. They are uncommon.
What happens to embryos less than 30 days old? dies and is resorbed
What happens to early fetus infected? (30-70 days) die and are mummified
What happens to a late fetus that is infected? develop lesions and survive to produce antibody to PPV
When does immunocompetence of pig fetuses start? 55-70 days
What are immunotolerant pigs? They are piglets that are born as infected but immune piglets that can pass the virus continuously or intermittently
How long can maternally immunity last? 4 months but in some pigs it can last up to 6-9 months
Is immunity lifelong? YES
Is is possible for some gilts to be seronegative at mating time to be susceptible to infection? YES
What is different about the porcine parvovirus from the others? It causes persistent infection with CHRONIC shedding.
Created by: lkollmeier