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Inclusion Body Rhinitis

How many swine in a herd carry the virus? up to 90%
This virus is highly cell associated. How is it transmitted? INHALATION. transplacental transmission in naive sows
Where is the primary site of virus replication? Nasal mucous glands and other cells of the URT
Viremia causes the virus to localize where? in MACROPHAGES, EPITHELIAL-TYPE CELLS, and ENDOTHELIAL CELLS
Endothelial cell damage and necrosis accounts for what? petechial hemorrhages and edema
What is anemia attributed to? bone marrow damage...widespread damage by virus causes death
The disease is seen in [this] age group of pigs, but it is most severe in piglets of [this] age. 2-10 weeks old. Less than 3 weeks of age.
What are the clinical features? sneezing, mucopurulent discharges can block nasal passages- hard to suckle and leads to rapid wt. loss and death. SMEDI.
What signs do older pigs (greater than 4 months) show? Subclinical
What is distinct about the pathology of this virus? BASOPHILIC INTRANUCLEAR inclusion bodies and CYTOMEGALY
How can you control this virus? Good management and abstention from introducing new stock during the mating period
Created by: lkollmeier