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RBC Morphology

Hematology, RBC morphology

QuestionAnswer
Acanthocyte irregularly spiculated, spur cells, may occur in cats with hepatic lipidosis, occasionally in dogs with liver disease.
NRBC nucleated red blood cells, normal in avians and reptiles, early release of immature cells (anemia) in dogs or cats.
Schistocyte fragmented RBCs, intravascular trauma, DIC, or iron deficiency.
Stomatocyte central pallor is slit-like, may be artifactual, associated with anemias, liver disease.
Crenated RBC shriveled RBC, spiculated, may occur with too much EDTA, slow drying of blood film.
Rouleaux formation stacked coin appearance, normal in horses, may be artifactual if blood is held too long or refrigerated.
Heinz bodies rounded projections, stain pale with wright's stain, <5% is normal in cats, increased with lymphosarcoma, hyperthyroidism, and diabetes mellitus in cats.
Howell-jolly bodies stain as blue dots, related to splenic removal or disorder.
Echinocyte regularly spiculated, artifactual, associated with slow drying of blood films or too much EDTA, may be associated with renal disease and lymphosarcoma in dogs.
Basophilic stippling presence of small, dark blue dots, usually characteristic of lead poisoning in dogs
Agglutination clumping formation, occurs in immune-mediated disorders
Created by: tarynsmethers