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gas
pharmacology
| Question | Answer |
|---|---|
| Thymol as preservative | Halothane |
| Cerebral blood flow increases. | Halothane |
| It causes dose dependent depression of cardiac output and drop in arterial blood pressure. | Halothane |
| Catecholamine induced arrhythmias are common | Halothane |
| Inspired concentration of 2 to 4% produce smooth rapid induction of anesthesia in all domestic animals | Halothane |
| Metabolized up to 19 to 22% | Halothane |
| Bromide peaks at 72 hours. | Halothane |
| Malignant hyperthermia, halothane is the most potent. | Halothane |
| Isoflurane is the similar to enflurane in general physical and chemical properties. | Isoflurane |
| Metabolized 0.17%, main metabolite are trifluroacetic acid and inorganic fluoride, renal toxicity is very remote. | Isoflurane |
| Now a days most commonly used in all clinical cases | Isoflurane |
| Has better cardiovascular function compared with other gas anesthetics, other than nitrous oxide. | Isoflurane |
| Respiratory depression is greater than halothane. | Isoflurane |
| Arrhythmias have not been reported and less likely to occur with catecholamines. | Isoflurane |
| Isomers of Isoflurane. | Enflurane |
| Causes seizer like activity, muscle twitching, head jerks. | Enflurane |
| Cardiovascular depression similar to halothane. | Enflurane |
| Metabolism 2.4 % | Enflurane |
| Metabolite is inorganic fluoride. | Enflurane |
| Renal toxicity is unlikely, but hepatitis has been reported. | Enflurane |
| It is a fluorinated ether and metabolized to free fluoride ions and hexafluoroisopropanol which is rapidly glucuronid in the liver. | Sevoflurane |
| Hepatotoxicity very low | Sevoflurane |
| Renal toxicity has been reported in man. | Sevoflurane |
| MAC 2.05 | Sevoflurane |
| Blood/Gas solubility 0.62. | Sevoflurane |
| Metabolism 3.0% | Sevoflurane |
| Rapid induction and very rapid recovery compared to isoflurane, but not as fast as desflurane. | Sevoflurane |
| Desflurane is a fluorinated methyl ethyl ether, differing from isoflurane only in the substitution of fluorine for chloride at the alpha ethyl carbon. | Desflurane |
| MAC 7.2 | Desflurane |
| Blood/Gas solubility 0.4 | Desflurane |
| It can boil at close to room temperature, therefore a special vaporizer produced is essential. | Desflurane |
| Metabolism 0.02 %, potential for toxicity is very low. | Desflurane |
| Very rapid induction and recovery compared to isoflurane and sevoflurane. | Desflurane |
Created by:
alljacks
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