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DU PA Inflam Dermato
Duke PA Common Inflammatory Dermatoses
| Question | Answer |
|---|---|
| a systemic, immunologic, genetic disease manifesting in skin and or joints | psoriasis |
| most common type of psoriasis, sharply defined erythematous scaling plaques, distribution somewhat symmetrical, duration is months to years | plaque psoriasis |
| red scaling papules coalesce to round-oval plaques, scale is adherent, silvery white, lesions occur at site of trauma, pruritus is variable, pustules may outline lesiona dn occur on palms and soles | psoriasis |
| drugs that exacerbate psoriasis | lithium, beta-blocking agents, antimalarials, systemic steroids |
| factors that flare psoriasis | streptococcal infection, injury or trauma, drugs, low humidity, emotional stress, overtreatment |
| small papules of short duration (weeks to months), usually children and young adults, many have streptococcal URI within 1-2 weeks of presentation (drop like) | Guttate Psoriasis |
| etiology of psoriasis | hyperproliferation of epidermis, increased growth altered differentiation, inflammation of epidermis and dermis, T-lymphocytes accumulate, cytokin-mediated inflammation |
| psoriasis associations | cardiovascular disease, depression, lymphoma |
| psoriasis treatment strategies | topical, phototherapy, sytemic |