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LAT Certification
Chapter 1
Question | Answer |
---|---|
What are the steps in the research process? | Define the Question, Formulate an objective framework, Establish a hypothesis, Create a research design, Identify variables, Collect and analyze data, Report data and conclusions |
What is the definition of research? | A systematic investigation to establish facts |
How is research funding obtained? | Grants, Contracts or Donations from Private or Public Sources |
What information must be included on a grant application? | A detailed description of research goals, the scientific basis of the study, a thorough review of relevant literature, any preliminary data and results, and all procedures to be performed |
What are the main public granting agencies in the US? | NIH and NSF |
What is the primary granting agency supporting biomedical research? | NIH |
Name some other federal agencies that provide grants | Department of Defense (DOD), Department of Energy (DOE), Department of Agriculture (USDA) and the National Aeronautics and Space Administration (NASA) |
Name two private foundations that fund research | American Heart Association and the American Cancer Society |
What does IACUC stand for? | Institutional Animal Care and Use Committee |
What are the AWA requirements for an IACUC composition? | Have at least 3 members: Chairperson, Veterinarian with training or experience in laboratory animal science and medicine, a member not associated with the institution (nonaffiliated or community member) |
What are the PHS requirements for an IACUC composition? | Have at least 5 members: Chairperson, Veterinarian, a practicing scientist with animal research experience, a nonscientist, community member |
What is the primary task of the IACUC? | Review the animal use protocols of research projects to ensure compliance with all relevant federal, state and local laws, regulations and institutional policies on animal welfare. |
What is the purpose of the protocol review? | Ensure the welfare of the animals used in the study and to ensure regulatory compliance |
What information does a typical animal use protocol contain? | Study rationale, justification for species and number of animals, evidence of review for 3Rs, list of personnel, complete description of procedures, criteria for timely intervention, intended method of euthanasia |
What is the goal of a post-approval monitoring program? | To ensure that IACUC-approved procedures are being followed |