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NHP, Lab, Intro

NHP, Lab, Intro - VTT 232

QuestionAnswer
A _________ facility has animal rooms that open directly onto a central corridor. Conventional
___________ facilities prevent cross contamination with unidirectional traffic flow. Double-corridor
What facility houses germ-free animals and requires shower and sterile clothing to enter? Barrier
A facility that requires staff to shower also before exiting with disposable autoclaved clothing to house zoonotic animals is called what? Containment facility
Animals must have __ to __ air changes per hour. 10 to 15
How many hours of light must lab animals have? 12 hours
What are some caging materials? Stainless steel, aluminum, plastic
What types of plastic are used? Polycarbonate (clear), polypropylene (opaque)
A ________ animal has unknown or undefined microflora. Conventional
A ________ _________ animal is axenic (no microflora in or on them) and germ free. Defined flora
A _______ animal has well-defined microflora. Gnotobiotic
Animals we know to not have something are _____ ______ _____. Specific pathogen free
What defines the order of Rodentia? Gnawing
What is a Mus Misculus? Mouse
Animal dealers must be licensed by the _____ and adhere to AWA standards. USDA
Purpose-bred animals must come from a USDA class ___ license. A
Animals from shelters are called class ___ dealers. B
What does Anthropoidea (simians) includes? Lesser and great apes, humans, new and old world primates
What are the most common great ape? Chimpanzees
Chimpanzees are closely related to humans on a ________ level. Molecular
Brains of _________ monkeys are organized similarly to humans. Rhesus
Are macacas old or new world primates? Old
Spider monkeys are used for ______ research. Malaria
What characteristics do new world primates have? Round skull, prehensile tail
What characteristics do old world primates have? Open down nasal passages, cheek pouches, flat skull, prominent brows, ischial callosities
Wild caught animals must be acclimated and quarantined for ___ days. 60
What are some environmental enrichments for primates? Toys, foraging for food, socialization
What are some PPE used with primates? Face shields or goggles, protective gloves, arm covers
What are some restraint techniques? Chemical, training, collar and pole, manual, squeeze cage
What is the most common site of primate blood draw? Femoral vein
Where is a TB test done in apes to minimize handling? Upper eyelid
_________/diarrhea is common among primate colonies, caused typically by bacteria. Gastroenteritis
_______ diseases, like gastroenteritis, is also common with primate colonies. Respiratory
What non-zoonotic diseases are common with primates? Filovirus (ebola), retroviruses (SIV), malaria (species specific)
The rhesus monkey is scientifically called ______________. Macaca mulatta
What are the suborders of NHP? Prosimians, anthropoidea
The chimpanzee is scientifically called _________________. Pan troglydites
The ____ was created to make a national plan for use of monkeys. IPSC
Squirrel monkeys are used for _____________. Anteriosclerosis
The only euthanasia method for NHPs is _______. Injection
What causes oral ulcers in people that can kill primates? Herpes hominis
What is the government agency that oversees the use of animals in an educational or research institution? USDA
Who has published the Guide for Care and use of Lab Animals? ILAR
What is the institutional group that evaluates animal use and inspects facilities? IACUC
What is the group that provides voluntary accreditation of biomedical facilities? AAALAC
What is research directed toward specific objectives such as new drug development? Applied research
Procedures that cause least stress, pain and anxiety (least impact on the animal) are called ________. Refinement
The use of fish and plants in research is an example of _________. Replacement
Who board certifies veterinarians who have reached the highest degree of proficiency in lab animal medicine? ACLAM
What is the minimum membership of an IACUC? 3 (public person, vet, chair)
The two most active animal liberation groups in the US are ______ and _______. PETA, ALF
No ______ alternatives to animal research exist. Complete
What are the goals of bio-medical research? A&P knowledge, examine disease process, control and treatment of disease
What factors influence outcomes of a research study? Intrinsic, extrinsic, dietary, experimental
________ means originating in the body. Intrinsic
What are intrinsic factors? Species, age, gender, genetics
_________ means outside the body. Extrinsic
What are some extrinsic factors? Ventilation, lighting, noise, humidity, environmental temperature
What are some dietary factors? Quality, amount availability, container cleanliness
Experimental factors include what? Surgical procedures, restraint, medications
Specific guidelines are mandated by places like the ____, that fund research. NIH
When labelled as "not tested on animals", every _________ is tested still even if the actual product has not been. Ingredient
What country has completely banned animal research? Nazi Germany
The ______ _______ _____ governs sale, handling, transport, care, education, research and exhibition. Animal Welfare Act (AWA)
The Animal Welfare Act applies to all warm blooded animals except ______________________. Farm animals and horses, birds, rats and mice if purpose bred, cold-blooded animals
Who enforces the AWA? USDA
________ is a part of USDA that annually inspects facilities. APHIS (Animal and Plant Health and Inspection Service)
The ____ can remove products from the market if product safety cannot be determined. EPA
The ____________ funds as well as conducts biomedical research. National Institute of House (NIH)
What are the 3 R's? Reduction, refinement, replacement
Created by: PimaVT